DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir94d and Grik5

DIOPT Version :9

Sequence 1:	NP_001138099.1	Gene:	Ir94d / 7354412	FlyBaseID:	FBgn0259193	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	XP_006228444.1	Gene:	Grik5 / 24407	RGDID:	2735	Length:	980	Species:	Rattus norvegicus

Alignment Length:	495	Identity:	91/495 - (18%)
Similarity:	170/495 - (34%)	Gaps:	110/495 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 IERRLDNSTVIFEKRLENLHGYEVPIALGGSSPRLIVYRDLEGKLIFSGPVGNFMKSFEQ----R 220
            :.:.|.|.|::....|||.:....|           .::.|.|...|.|...:.::...:    |
  Rat   408 LSQTLANKTLVVTTILENPYVMRRP-----------NFQALSGNERFEGFCVDMLRELAELLRFR 461

  Fly   221 YNCRLVQ------PYPFDESAISPARDLIASVQNGSVQIALGAIYPQ-VPYTGYSYPIELMSWCL 278
            |..|||:      |.| :.|......:|| :.|...:.:|...|..: .....:|.|...:...:
  Rat   462 YRLRLVEDGLYGAPEP-NGSWTGMVGELI-NRQKADLAVAAFTITAEREKVIDFSKPFMTLGISI 524

  Fly   279 MMPV-PEEVPHSQLYSMVFSPMAFGITIVAMVLISLTLSMALRLHGYRVSFSEYFLHDSCLR--- 339
            :..| ....|....:...|||..:...::|.:.:|..|.:|.||..|     |::....|||
  Rat   525 LYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPY-----EWYNPHPCLRARP 584

  Fly   340 -----------------GVLSQSFYEVLRAPALIKAMYLVICLLG------LLITSWYNSYFSTF 381
                             |...|...|::  |..:...    |:.|      |:|.|.|.:..:.|
  Rat   585 HILENQYTLGNSLWFPVGGFMQQGSEIM--PRALSTR----CVSGVWWAFTLIIISSYTANLAAF 643

  Fly   382 VT-SAPRFPQLTSYESIRHSNIKIVIWKPEYEMLLFFSENMEKYSSIFQLQEDYKEFLHLRDS-- 443
            :| .....|..::.:....:||:.........|..|.:...:.|..::...:..:..:.::.:
  Rat   644 LTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEE 708

  Fly   444 -----FDTRYGYMMPMEKWSLMKEQQRVFSSPLFSLQDDLCVFHTVPIVFPMVKNSIFKEPFDRL 503
                 .::||.:::.    |.|.|..|..:..|..:..   :..|......|...|.|::.....
  Rat   709 GIARVLNSRYAFLLE----STMNEYHRRLNCNLTQIGG---LLDTKGYGIGMPLGSPFRDEITLA 766

  Fly   504 ILDVTATGLLSRWRDMSFTEMIK-----AGQLGLEDRGHPKEFRAMKVGDLIQIWRFVGWMLGLA 563
            ||.:.....|         |::|     .|:...|:....|......:|.:     ||..:.||.
  Rat   767 ILQLQENNRL---------EILKRKWWEGGRCPKEEDHRAKGLGMENIGGI-----FVVLICGLI 817

  Fly   564 TIVFLLELICFWR-------------HKMWQNMKY-MFCR 589
            ..||:..:...|.             .:|.|.::: :.||
  Rat   818 IAVFVAVMEFIWSTRRSAESEEVSVCQEMLQELRHAVSCR 857

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
Grik5	XP_006228444.1	PBP1_iGluR_Kainate_KA1_2	23..401	CDD:380616
Grik5	XP_006228444.1	Periplasmic_Binding_Protein_Type_2	414..785	CDD:389745	75/410 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350204
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840