Protein Alignment Ir94d and Grin3a

DIOPT Version :9

• Sequence 1: NP_001138099.1
• Gene: Ir94d / 7354412
• FlyBaseID: FBgn0259193
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001263284.1
• Gene: Grin3a / 242443
• MGIID: 1933206
• Length: 1135
• Species: Mus musculus
• Alignment Length: 607
• Identity: 116/607 - (19%)
• Similarity: 198/607 - (32%)
• Gaps: 199/607 - (32%)

  Fly    26 IHHLNR-------ELKIEYVLLL--GNFDTTWLDILWQLPVSVLQIKEH--SRETYSLLENPSHN 79
            :.:|||       .|.:|.|:.:  |         |..||:........  |.:.:|.|::..|.
Mouse   132 VENLNRVEGLLPYNLSLEVVMAIEAG---------LGDLPLMPFSSPSSPWSSDPFSFLQSVCHT 187

  Fly    80 VLT------IAFVNDSPEDI-LEILYRNLRMLNTQPVLLVIRKSTIRVNSLLEWCWHHQLLKVVA 137
            |:.      :||.....|.: |:::...|.:    |||.::|               |:..:
Mouse   188 VVVQGVSALLAFPQSQGEMMELDLVSSVLHI----PVLSIVR---------------HEFPR--- 230

  Fly   138 IAQDFMESLIVYSYNPFPVLQFIERRL--DNSTVIFEKRLENLHGYEVPIALGGSSPRLIVYRDL 200
                       .|.||..:...:|..|  |....:....:.|.:.:.:          |:...|.
Mouse   231 -----------ESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSL----------LLCQEDW 274

  Fly   201 EGKLIFSGPVGNFMKSFEQRYNCRLVQPYPFDESAI------SPARDLIASVQNGSVQIALGAIY 259
            .        :.:|:...|......|       ||.|      |..:||::.:|
Mouse   275 N--------ITDFLLLTENNSKFHL-------ESIINITANLSSTKDLLSFLQ------------ 312

  Fly   260 PQVPYTGYSYPIELMSWCLMMPVPEEVPHSQLYSMVFSP----MAFGITIVAMVLISLTLSMALR 320
            .|:.....|.|..:|..|.|..:.:....|..:.:  ||    ...|.:.....|.:..|.:.|.
Mouse   313 VQLENIRNSTPTMVMFGCDMGSIRQIFEMSTQFGL--SPPDLHWVLGDSQNVEELRTEGLPLGLI 375

  Fly   321 LHGYRV-SFSEYFLHDS---CLRGVLSQSFY--EVLRAPALIKAMYLVICLLGLLITSWYNSYFS 379
            .||... |..||::.|:   ..|.|.:.:..  |:...|:.:..|.:....|    ||  ..|.|
Mouse   376 AHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNL----TS--GQYLS 434

  Fly   380 TFVTSAPRFPQLTSYESIRHSNI-----KIVIWKPEYEML--------------------LFFSE 419
            .|:.:. .|..|:....::.|.|     ...||..:|:.:                    ..:.|
Mouse   435 RFLANT-TFRGLSGSIKVKGSTIVSSENNFFIWNLQYDPMGKPMWTRLGSWQGGRIVMDSGIWPE 498

  Fly   420 NMEKYSSIFQLQEDYKEFLHLRDSFDTRYGYMM------------------PMEKWSLMKEQQRV 466
            ..:::.:.|.    :...||||......:.::.                  ||...|.:.:.  :
Mouse   499 QAQRHKTHFH----HPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSILDS--L 557

  Fly   467 FSSPLFSLQDDLCVFHTVPIVFPMVKNSIFKEPFDRLILDVTATGLLSRWRDMSF---TEMIKAG 528
            ||| |.|..|      ||||.|   |...:....|  :|:..|       .||:|   ..::..|
Mouse   558 FSS-LHSSND------TVPIKF---KKCCYGYCID--LLEQLA-------EDMNFDFDLYIVGDG 603

  Fly   529 QLGLEDRGHPKEFRAMKVGDLI 550
            :.|....||....    ||||:
Mouse   604 KYGAWKNGHWTGL----VGDLL 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
Grin3a	NP_001263284.1	PBP1_iGluR_NMDA_NR3	30..497	CDD:107372	81/452 (18%)
		PBP2_iGluR_NMDA_Nr3	512..908	CDD:270438	33/135 (24%)
		Lig_chan	676..942	CDD:278489
		PPP2CB binding site. /evidence=ECO:0000250|UniProtKB:Q9R1M7	951..987
		GIT1-binding. /evidence=ECO:0000250|UniProtKB:Q9R1M7	1082..1115

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846525
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930