DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir94d and Grin3b

DIOPT Version :9

Sequence 1:	NP_001138099.1	Gene:	Ir94d / 7354412	FlyBaseID:	FBgn0259193	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_579842.2	Gene:	Grin3b / 170796	RGDID:	621705	Length:	1002	Species:	Rattus norvegicus

Alignment Length:	208	Identity:	47/208 - (22%)
Similarity:	82/208 - (39%)	Gaps:	69/208 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 RLVQPYPFDESAISPARDLIASVQNGSVQIALGAIYPQVPYTGYSYPIELMSWCLMMPVPEEVPH 288
            |:|:.:|      .|.|  :.:....||::|  |:.|:.|    :....::: .|..|.| .:||
  Rat    20 RVVRGHP------QPCR--VPTRAGASVRLA--ALLPRAP----AARARVLA-ALATPAP-RLPH 68

  Fly   289 SQLYSM--VFSP------MAFGITIVAM---VLISLTLSMA---LRLHGYRVSFSEYFLHDSCLR 339
            :....:  |.||      :|.|:..|..   |:.|:....|   |||..:..:.:|     :.:.
  Rat    69 NLSLELVAVASPTRDPASLARGLCQVLAPPGVVASIAFPEARPELRLLQFLAAATE-----TPVV 128

  Fly   340 GVLSQSFYEVLRAP---------------------ALIKA-----MYLVICLL---GLLITSWYN 375
            .||.:.....|.||                     :|::|     :.||:|.:   |.|:|.|.|
  Rat   129 SVLRREVRTALGAPTPFHLQLDWASPLETILDVLVSLVRAHAWEDIALVLCRVRDPGSLVTLWTN 193

  Fly   376 SYFSTFVTSAPRF 388
                 ..:.||:|
  Rat   194 -----HASQAPKF 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
Grin3b	NP_579842.2	PBP1_iGluR_NMDA_NR3	21..405	CDD:107372	46/207 (22%)
		PBP2_iGluR_NMDA_Nr3	414..808	CDD:270438
		Lig_chan	576..842	CDD:278489
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	882..910
		Involved in the trafficking and surface expression of NMDARs. /evidence=ECO:0000250	951..984
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350192
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930