Protein Alignment Ir94d and Grin2d

DIOPT Version :9

• Sequence 1: NP_001138099.1
• Gene: Ir94d / 7354412
• FlyBaseID: FBgn0259193
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: XP_036008580.1
• Gene: Grin2d / 14814
• MGIID: 95823
• Length: 1345
• Species: Mus musculus
• Alignment Length: 629
• Identity: 111/629 - (17%)
• Similarity: 213/629 - (33%)
• Gaps: 217/629 - (34%)

  Fly    45 DTTWLDILWQLPVSVLQIKEHSRETYSLLENPSHNV--LTIAFVNDSPEDILEILYRNLRMLNTQ 107
            |.|| :::.......|::|......|.....|..:.  ||:|.:.:.|..|:|         ...
Mouse   397 DRTW-EVVGSWEQQTLRLKYPLWSRYGRFLQPVDDTQHLTVATLEERPFVIVE---------PAD 451

  Fly   108 PVLLVIRKSTIRVNSLLEWCWHHQLLKVVAIAQDFMESLIVYSYNPFPVLQFIERRLDNSTVI-F 171
            |:.....:.::...|.|...  |.|               |...:|.|.....|:|......| .
Mouse   452 PISGTCIRDSVPCRSQLNRT--HSL---------------VAPRSPPPDAPRPEKRCCKGFCIDI 499

  Fly   172 EKRLENLHG--YEVPIALGGSSPRLIVYRDLEGKLIFSGPVGNFMKSFEQRYNCRLVQ------- 227
            .|||.:..|  |::.:...|...:.|     :|  :::|.:|   :.|.||.:..:..
Mouse   500 LKRLAHTIGFSYDLYLVTNGKHGKKI-----DG--VWNGMIG---EVFYQRADMAIGSLTINEER 554

  Fly   228 ------PYPFDESAISPARDLIASVQNGSVQIALGAIYPQVPYTGYSYPIELMSWCLMMPVPEEV 286
                  ..||.|:.||    ::.:..||:|.                 |...:::..:||.....
Mouse   555 SEIVDFSVPFVETGIS----VMVARSNGTVS-----------------PSAFLAFAWLMPPMSPE 598

  Fly   287 PHS-QLYSMVFSPMAFGITIVAMVL--------ISLTLSMALRLHGYRVSFSEYFLHDSCLRGVL 342
            |:| .::.|:|   ...:|:||:.:        :....|:|.   |.|...|.:.:..|
Mouse   599 PYSPAVWVMMF---VMCLTVVAVTVFIFEYLSPVGYNRSLAT---GKRPGGSTFTIGKS------ 651

  Fly   343 SQSFYEVLRAPALIKAMYLVICLLGLLITSWYNSYFSTFVTSAP-RFPQLTSYESIRHSNIKIVI 406
                                |.||..|:          |..|.| ..|:.|:      |.|.:::
Mouse   652 --------------------IWLLWALV----------FNNSVPVENPRGTT------SKIMVLV 680

  Fly   407 WKPEYEMLLF---FSENMEKYSSIFQLQEDYKEFL------------------------------ 438
            |  .:..::|   ::.|:    :.|.:||:|.:.:
Mouse   681 W--AFFAVIFLASYTANL----AAFMIQEEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEK 739

  Fly   439 HLRDSFDTRYGYMM----PMEKWSLM-----KEQQRVFSSPLFSL---QDDLC---------VFH 482
            ::|.::...:.||:    |..:.:|.     |....::.:.:.:.   :|:.|         ||.
Mouse   740 NIRSNYPDMHSYMVRYNQPRVEEALTQLKAGKLDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFA 804

  Fly   483 TVPIVFPMVKNSIFKEPFDRLILDVTATGLLSRWRDMSFTEMIKAGQLGLEDRGHPKEFRAMK-- 545
            |......:.|.|.:|.|.|..:|.......:         ||::  :|.|....|..:...|.
Mouse   805 TTGYGIALHKGSRWKRPIDLALLQFLGDDEI---------EMLE--RLWLSGICHNDKIEVMSSK 858

  Fly   546 --VGDLIQIWRFVGWMLGLATIVFLLELICFWR--------HKM 579
              :.::..::..:...:||:.:||..|.:.:||        |:|
Mouse   859 LDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLRHCLGPTHRM 902

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
Grin2d	XP_036008580.1	Periplasmic_Binding_Protein_type1	<156..415	CDD:415822	4/18 (22%)
		PBP2_iGluR_NMDA_Nr2	432..849	CDD:270436	93/538 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846647
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840