Protein Alignment Ir94d and Grin2c

DIOPT Version :10

• Sequence 1: NP_001138099.1
• Gene: Ir94d / 7354412
• FlyBaseID: FBgn0259193
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: XP_017169765.1
• Gene: Grin2c / 14813
• MGIID: 95822
• Length: 1307
• Species: Mus musculus
• Alignment Length: 666
• Identity: 131/666 - (19%)
• Similarity: 220/666 - (33%)
• Gaps: 232/666 - (34%)

  Fly    53 WQLP--------VSVLQIKEHS-RETYSLLENPSHNVLTIAFVNDSP-EDILEILYRNLRMLN-- 105
            |:|.        |::|.:..|| |..|..|..|:.:..:    :..| ....|..||:|  ||
Mouse   343 WRLSLRQKVRDGVAILALGAHSYRRQYGTLPAPAGDCRS----HPGPVSPAREAFYRHL--LNVT 401

  Fly   106 --------------TQPVLLVIRKSTIRVNSLLEW----CWHHQLLKVVAIAQDFMESLI--VYS 150
                          .||.::||..:..|:     |    .|.|.:|        :|:..:  .||
Mouse   402 WEGRDFSFSPGGYLVQPTMVVIALNRHRL-----WEMVGRWDHGVL--------YMKYPVWPRYS 453

  Fly   151 YNPFPVLQFIERRLDNSTVIFEKRLENLHGYEVPIALGGSSPRLIVYRDLEGKLIFSGPVGNFMK 215
            .:..||:.  .|.|..:|:  |:|                 |.:||.....|.   .|.|.|.:.
Mouse   454 TSLQPVVD--SRHLTVATL--EER-----------------PFVIVESPDPGT---GGCVPNTVP 494

  Fly   216 SFEQRYNCRLVQPYPFDESAISPARDLIASVQNGSVQIALGAIYPQVPYTGYSYPIELMS----- 275
                   ||....:.|....|:|...|...      ...:..:........:||.:.|::
Mouse   495 -------CRRQSNHTFSSGDITPYTKLCCK------GFCIDILKKLAKVVKFSYDLYLVTNGKHG 546

  Fly   276 ------WCLMMPVPEEVPHSQLYSMVFSPMAFGITIVAMVLISLTLS-MALRLHGYRVSFSEYFL 333
                  |..|:   .||.:.:      :.||.|         |||:: ....:..:.|.|.|..:
Mouse   547 KRVRGVWNGMI---GEVYYKR------ADMAIG---------SLTINEERSEIIDFSVPFVETGI 593

  Fly   334 HDSCLR--GVLSQSFYEVLRAPALIKAMYLVICLLGLLITSWYNSYFSTF-----VTSAPRF--P 389
            .....|  |.:|.|.:....:|| :..|..|:||..:.||.:...|||..     :|...:.  |
Mouse   594 SVMVARSNGTVSPSAFLEPYSPA-VWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTKGKKSGGP 657

  Fly   390 QLTSYESI-------------------RHSNIKIVIWKPEYEMLLF---FSENMEKYSSIFQLQE 432
            ..|..:|:                   ..|.|.:::|  .:..::|   ::.|:    :.|.:||
Mouse   658 SFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVW--AFFAVIFLASYTANL----AAFMIQE 716

  Fly   433 DY---------KEFLHLRDSFDT-RYGYMMPMEKWS-------------LMKEQQRVFSSPLFSL 474
            .|         |:|...:|.:.. |:| .:|.....             ::|..||.....|.||
Mouse   717 QYIDTVSGLSDKKFQRPQDQYPPFRFG-TVPNGSTERNIRSNYRDMHTHMVKFNQRSVEDALTSL 780

  Fly   475 --------------------------QDDLC---------VFHTVPIVFPMVKNSIFKEPFDRLI 504
                                      :|:.|         ||.|......|.|:|.:|...|..:
Mouse   781 KMGARHVSRKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLAL 845

  Fly   505 LDVTATGLLSRWRDMSFTEMIKAGQLGLEDRGHPKEFRAMK----VGDLIQIWRFVGWMLGLATI 565
            |.....|           |..|...:.|....|.::...|.    :.::..::..:...:|||.:
Mouse   846 LQFLGDG-----------ETQKLETVWLSGICHNEKNEVMSSKLDIDNMAGVFYMLLVAMGLALL 899

  Fly   566 VFLLELICFW--RHKM 579
            ||..|.:.:|  ||.:
Mouse   900 VFAWEHLVYWKLRHSV 915

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
Grin2c	XP_017169765.1	PBP1_iGluR_NMDA_NR2	90..446	CDD:380601	27/121 (22%)
		PBP2_iGluR_NMDA_Nr2	462..868	CDD:270436	89/477 (19%)
		NMDAR2_C	905..>980	CDD:463148	3/11 (27%)