Protein Alignment Ir94d and GRIN3B

DIOPT Version :9

• Sequence 1: NP_001138099.1
• Gene: Ir94d / 7354412
• FlyBaseID: FBgn0259193
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_619635.1
• Gene: GRIN3B / 116444
• HGNCID: 16768
• Length: 1043
• Species: Homo sapiens
• Alignment Length: 488
• Identity: 90/488 - (18%)
• Similarity: 160/488 - (32%)
• Gaps: 149/488 - (30%)

  Fly   132 LLKVVAIAQDFMESLIVYSYNPFPVLQFIERRLDNSTVIFEKRLENLHGYEVPIALGGSSP---- 192
            ||.:..:|:..:|:.|      ..::|.:.|.|.::..:..||..    ...|:..|...|
Human   278 LLALGEVARPPLEAAI------HDIVQLVARALGSAAQVQPKRAL----LPAPVNCGDLQPAGPE 332

  Fly   193 -------RLIVYRDLEGKLIFSGPV---GNFMKSFEQRYNCRLVQPYPFDESAISPARDLIASVQ 247
                   |.:.....:|:   :|||   |:......:.:....::..|..    :||...:.|.:
Human   333 SPGRFLARFLANTSFQGR---TGPVWVTGSSQVHMSRHFKVWSLRRDPRG----APAWATVGSWR 390

  Fly   248 NGSVQIALG--AIYPQVPYTGYSYPIELMSWCLMMPV-----PEE---VPHSQL----------- 291
            :|.:.:..|  :..|..|.....:|...:...|..|.     |:|   .|..||
Human   391 DGQLDLEPGGASARPPPPQGAQVWPKLRVVTLLEHPFVFARDPDEDGQCPAGQLCLDPGTNDSAT 455

  Fly   292 YSMVFSPMAFGITIVAMVLISLTLSMALR--LHGYRVSFSEYFLHDSCL-----------RGVLS 343
            ...:|:.:|.|           :...|||  .:||.:...|....|:..           .|.|.
Human   456 LDALFAALANG-----------SAPRALRKCCYGYCIDLLERLAEDTPFDFELYLVGDGKYGALR 509

  Fly   344 QSFYEVLRAPALIKAMYLVICLLGL-----LITSWYNSYFSTFV--------TSAPRFPQLTSYE 395
            ...:..|....|....::.:....:     .:..:.:.:|||.:        |::|
Human   510 DGRWTGLVGDLLAGRAHMAVTSFSINSARSQVVDFTSPFFSTSLGIMVRARDTASP--------- 565

  Fly   396 SIRHSNIKIVIWKPEYEMLLFFSENMEKYSSIFQLQEDYKEFLHLRDSFDTRYGYMMPMEKWSLM 460
                  |...:|...:...|          .:|..       |||...|.|.|.:..|.......
Human   566 ------IGAFMWPLHWSTWL----------GVFAA-------LHLTALFLTVYEWRSPYGLTPRG 607

  Fly   461 KEQQRVFSSPLFSLQDDLCVFHTVPIVF-PMVKNSIFKEPFDRLILDVTATG---LLSRWR---- 517
            :.:..|||   :|...:||    ..|:| ..|.:...|.|..||::::.|..   :||.:.
Human   608 RNRSTVFS---YSSALNLC----YAILFRRTVSSKTPKCPTGRLLMNLWAIFCLLVLSSYTANLA 665

  Fly   518 -----DMSFTEMIKAGQLGLED--RGHPKE-FR 542
                 |.:|.|:     .|:.|  ..||.: ||
Human   666 AVMVGDKTFEEL-----SGIHDPKLHHPAQGFR 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
GRIN3B	NP_619635.1	PBP1_iGluR_NMDA_NR3	19..405	CDD:107372	25/143 (17%)
		PBP2_iGluR_NMDA_Nr3	415..808	CDD:270438	63/334 (19%)
		Lig_chan	576..842	CDD:278489	34/147 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156254
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930