Protein Alignment Ir94d and grin3b

DIOPT Version :10

• Sequence 1: NP_001138099.1
• Gene: Ir94d / 7354412
• FlyBaseID: FBgn0259193
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 90/563 - (15%)
• Similarity: 174/563 - (30%)
• Gaps: 176/563 - (31%)

  Fly    13 LLSPGGD----------SFYHSLIHHLNRELKIEYVLLL---GNFDT----TWLDILWQLPVSVL 60
            |.||.|.          .:...|:..|:.:|:.::.|.:   |.:..    .|..::.
 Frog   467 LNSPNGSVPLEYKTCCYGYCIDLLEKLSEDLRFDFELYIVGDGKYGARKGDRWTGLVG------- 524

  Fly    61 QIKEHSRETYSLLENPSHNVLTIAFVNDSPEDILEILYRNLRMLNTQP-------VLLVIRKSTI 118
                      .||...:|..:|...:|.:...:::.         |.|       :|:.:|.:..
 Frog   525 ----------DLLSGAAHMAVTSFSINSARSTVIDF---------TSPFYSTSLGILVRMRDTAS 570

  Fly   119 RVNSLLEWCWHHQL-------LKVVAIAQDFMESLIVYSYNPFPVLQFIERRLDNSTVIF--EKR 174
            .:.:.: |..|..:       |.:.|:...|.|....:...|..         .|.|.||  ...
 Frog   571 PIGAFM-WPLHWSMWVGIFVALHITALFLTFYEWKSPFGMTPHG---------RNRTKIFSYSSA 625

  Fly   175 LENLHGYEVPIALGGSSPRLIVYRDLEG------KLIFSGPVGNFM------KSFEQRYNCRLVQ 227
            |...:.......:...:|:....|.|..      .|:.|....|..      |:||
 Frog   626 LNLCYAILFGRTVSSKTPKCCTGRVLMNLWAIFCLLVLSSYTANLAAVMVGDKTFE--------- 681

  Fly   228 PYPFDESAISPARDLIASVQNGSVQIALGAIYPQ--VPYTGYSYPIELMSWCLMMPVPEEVPHSQ 290
                   |:|...|  ..:.:.|.....|.::..  ..|...|:| |:.::.....||  .....
 Frog   682 -------ALSGIHD--PKLHHPSQGFRFGTVWESSAEQYIKKSFP-EMHNYMRKFSVP--ATSDG 734

  Fly   291 LYSMVFSPMAFGITIVAMVLIS-----------LTLSMALRLHGYRV----------SFSEYF-- 332
            ::.:...|......|:...|:.           ||:.....:.||.:          :.||:.
 Frog   735 VHLLKTDPPTLNAFIMDKALLDYEVSIDSDCKLLTIGKPFAIEGYGIGLPQNSPLTSNISEFISR 799

  Fly   333 ---------LHDSCLRGV-LSQSFYEVLRAPAL----IKAMYLVICL--LGLLITSWYNSYFSTF 381
                     |||...:.| ..:..|.|.....:    ...:::::|:  .|.|:||.........
 Frog   800 YKSSGFMDTLHDKWYKMVPCGKRVYAVTETLQMGIYHFSGLFVLLCIGFCGSLLTSLMERVVYHL 864

  Fly   382 VTSAPRFPQLTSYESIRHSNIKIVIWKPEYEMLLFFSENME----KYSSIFQLQEDYKEFLHLRD 442
            :  .||..:...::...|::.||      :..|....|:.:    |.:....||:|
 Frog   865 I--LPRIRRRRRFKYWLHTSQKI------HRALNMTCEDQDALSPKLNKRCNLQKD--------- 912

  Fly   443 SFDTRYGYMMPMEKWSLMK-----EQQRV-FSSPLFSLQDDLC 479
                  ....|...|:.::     :::|| |:....|.::.||
 Frog   913 ------ATGAPQSVWNNLRRTPAHQERRVHFNLEKASAREGLC 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	63/403 (16%)
		Lig_chan	580..847	CDD:459656	47/296 (16%)