Protein Alignment Ir94d and grin2cb

DIOPT Version :9

• Sequence 1: NP_001138099.1
• Gene: Ir94d / 7354412
• FlyBaseID: FBgn0259193
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: XP_009305071.2
• Gene: grin2cb / 100333648
• ZFINID: ZDB-GENE-100308-2
• Length: 1328
• Species: Danio rerio
• Alignment Length: 787
• Identity: 137/787 - (17%)
• Similarity: 248/787 - (31%)
• Gaps: 305/787 - (38%)

  Fly     9 VALVLLSPGGDSFYHSLIHHLNRELKIEYVLLLGNF-DTTWLDILWQLPVSVLQIKEHSRETYSL 72
            |.:..|.||.::|             ::|:   .:| ||::  .||:|
Zfish   174 VVITSLYPGYETF-------------VDYI---RSFTDTSY--FLWEL----------------- 203

  Fly    73 LENPSHNVLTIAF---VNDSPEDILEILYRNLRMLNTQPVLLVIRKSTIRVNS--LLEWCWHHQL 132
                 .:||:...   .||         .|..|:|.             :|:|  .|.:|.|.:.
Zfish   204 -----QDVLSFEMSVGAND---------IRTRRLLQ-------------QVDSQVYLVYCSHEEA 241

  Fly   133 LKVVAIAQD----------FMESLIVYSYNP-------FPV----------LQFIERRLDNSTVI 170
            ..:..:|.|          .:.||.|  .||       |||          .:.:.:|:.....|
Zfish   242 QYLFRMASDVGLLGPGYIWIVPSLAV--GNPEAAPPASFPVGVISIITDRWRKTLRQRVREGVAI 304

  Fly   171 FEKRLENLHGYEVPIALGGSSPRLIVYRDLEGKLIFSGPVGNFMKS--FEQRYNCRLVQ---PYP 230
            ..|.:.:.|.:.      |..|        ||....|.||.::..:  |....|.....   .:.
Zfish   305 IVKGVHSFHKHR------GFIP--------EGHSDCSSPVKSYANNSLFRHMLNVSWEHKDLSFN 355

  Fly   231 FDESAISPAR-----------DLIASVQNGSVQIALGAIYPQVP-YTGYSYPIE----------- 272
            .|....:|:.           |.:.|.:.|.:|:.    ||..| |..:..|:.
Zfish   356 SDGYLTNPSMVIIALDRENHWDKVGSYEGGILQMR----YPVWPRYGSFLEPVSDNRHLTVATLE 416

  Fly   273 ------------LMSWCLMMPVP---------EEVPHSQLYSMVFSPMAFGITIVAMVLISLTLS 316
                        ....|:...||         ..:.|::.|:.:.. ..|.|.|:..:..::..|
Zfish   417 ERPFVIVESVDPATGTCVRNTVPCRRQSNRTESIIGHTEPYTKLCC-KGFCIDILKKLSRTIKFS 480

  Fly   317 MALRL-----HG---------------YR------------------VSFSEYFLHDSC------ 337
            ..|.|     ||               |:                  |.||..|:....
Zfish   481 YDLYLVTNGKHGKMVRGVWNGMIGEVFYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVAR 545

  Fly   338 LRGVLSQSFYEVLRAPALIKAMYLVICLLGLLITSWYNSYFS------TFVTS-APRFPQLTSYE 395
            ..|.:|.|.:....:|| :..|..|:||..:.:|.:...|||      :.|:: ||..|..|..:
Zfish   546 SNGTVSPSAFLEPYSPA-VWVMMFVMCLTVVAVTVFVFEYFSPVGYNRSLVSAKAPGGPTFTIGK 609

  Fly   396 SI-------------------RHSNIKIVIWKPEYEMLLF---FSENMEKYSSIFQLQEDY---- 434
            |:                   ..|.|.:::|  .:..::|   ::.|:    :.|.:||.|
Zfish   610 SVWLLWGIVFNNSVPIENPKGTTSKIMVLVW--AFFAVIFLASYTANL----AAFMIQEQYIDTV 668

  Fly   435 -----KEFLHLRDSFDT-RYGYM------------MPMEKWSLMKEQQRVFSSPLFSL------- 474
                 |:|...::.:.. |:|.:            .|.....::|..|:.....|.||
Zfish   669 SGLSDKKFQKPQEHYPPFRFGTVPNGSTERNIRSNYPDMHTHMIKYNQKGVEEALNSLKTGKLDA 733

  Fly   475 -------------QDDLC---------VFHTVPIVFPMVKNSIFKEPFDRLILDVTATGLLSRWR 517
                         :|:.|         ||.|......:.|:|.:|.|.|..:|.....|
Zfish   734 FIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKDSRWKRPIDLALLQFLGDG------ 792

  Fly   518 DMSFTEMIKAGQLGLEDRGHPKEFRAMKVGDLIQIWRFVGWMLGLATIVFLLELICFW--RHKMW 580
            |....|.:....:...::......: :.:.::..::..:...:||:.:||..|.:.:|  ||.:.
Zfish   793 DTQRLETVWLSGICQNEKNEVMSSK-LDIDNMAGVFYMLLVAMGLSLLVFAWEHLLYWKLRHSVH 856

  Fly   581 QNMKYMF 587
            ::.:..|
Zfish   857 KSDRLDF 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir94d	NP_001138099.1	None
grin2cb	XP_009305071.2	PBP1_iGluR_NMDA_NR2	37..396	CDD:107373	55/303 (18%)
		PBP2_iGluR_NMDA_Nr2	407..808	CDD:270436	70/414 (17%)
		NMDAR2_C	845..>932	CDD:313729	4/19 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591841
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930