DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42391 and MBP1

DIOPT Version :9

Sequence 1:	NP_001137671.1	Gene:	CG42391 / 7354405	FlyBaseID:	FBgn0259737	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_010227.1	Gene:	MBP1 / 851503	SGDID:	S000002214	Length:	833	Species:	Saccharomyces cerevisiae

Alignment Length:	195	Identity:	40/195 - (20%)
Similarity:	76/195 - (38%)	Gaps:	36/195 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKLLVFNFIQTIPLQLRNNFKSKV-----KARPISYSLGTLHKHHTNFSTELENTINSESNFKN 60
            ||.:...::| |.|.|:..|....:     ..:.::.....||:.|.|....|:.|:.|.|..|.
Yeast   598 MSPVSPSDYI-TYPSQIATNISRNIPNVVNSMKQMASIYNDLHEQHDNEIKSLQKTLKSISKTKI 661

  Fly    61 ISNL--IKFVRQHSKWYRDNDCINRHYFNYILLDPRVTNNLKERASQLHLMDVWYTFLRAIFYVG 123
            ..:|  ::.:::.||........|..:.....|..:.|..|::|..:         :.|.|
Yeast   662 QVSLKTLEVLKESSKDENGEAQTNDDFEILSRLQEQNTKKLRKRLIR---------YKRLI---- 713

  Fly   124 KGKATRPYVHLKNAQKLVDE----TNNITLVKD----PKLAL-----IVSIWKANRGVLLIRAFQ 175
              |....|.......||:::    |.|.|:.||    .:|.|     ::.:.:.|:...|::.|:
Yeast   714 --KQKLEYRQTVLLNKLIEDETQATTNNTVEKDNNTLERLELAQELTMLQLQRKNKLSSLVKKFE 776

Fly 176 175
Yeast 777 776

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42391	NP_001137671.1	Peptidase_S80	<37..>101	CDD:305105	16/65 (25%)
CG42391	NP_001137671.1	GIY-YIG_COG3680_Meta	85..200	CDD:198401	20/104 (19%)
MBP1	NP_010227.1	KilA-N	22..93	CDD:367917
		ANKYR	363..544	CDD:223738
		ANK repeat	396..425	CDD:293786
		ANK repeat	427..510	CDD:293786
		ANK repeat	512..543	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900