DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42391 and ANKRD53

DIOPT Version :9

Sequence 1:NP_001137671.1 Gene:CG42391 / 7354405 FlyBaseID:FBgn0259737 Length:253 Species:Drosophila melanogaster
Sequence 2:NP_001108588.1 Gene:ANKRD53 / 79998 HGNCID:25691 Length:530 Species:Homo sapiens


Alignment Length:195 Identity:41/195 - (21%)
Similarity:67/195 - (34%) Gaps:66/195 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    95 VTNNLKERASQLHLM---DVWYTFLRAIFY-VGKGKATRPYVHLKNAQKLVDETNNITLVKDPKL 155
            :|||.:   :.|||:   |.....|..|:| :.||...       |||.....|......:|..|
Human   170 LTNNSQ---TPLHLVIHRDNTTVALPCIYYLLEKGADL-------NAQTCNGSTPLHLAARDGLL 224

  Fly   156 ALIVSIWKANRGVLLIRAFQGISSQDAQTREASIIDALGMNHLTNRRLGFYYGRARSLSD----K 216
            ..:         .:|:::...:.:|          ||:|...:...::..:...||.|.|    |
Human   225 DCV---------KVLVQSGANVHAQ----------DAMGYKPIDFCKIWNHRACARFLKDAMWKK 270

  Fly   217 ERKYLGIALLYKLMMK---------FLAKEEKE----------------LFP----LKNTKAAMA 252
            ::|.....:....|.|         :|.:.:||                |.|    :.|||.|.|
Human   271 DKKDFAREMTKMKMFKSQLTLMEHNYLIEYQKEHKILREAAIRKWLHGKLHPGHSLVSNTKQARA 335

  Fly   253  252
            Human   336  335

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CG42391NP_001137671.1 Peptidase_S80 <37..>101 CDD:305105 3/5 (60%)
GIY-YIG_COG3680_Meta 85..200 CDD:198401 23/108 (21%)
ANKRD53NP_001108588.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..99
Ank_4 112..160 CDD:290365
ANK 136..263 CDD:238125 25/121 (21%)
ANK 1 139..169