DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42391 and ank1b

DIOPT Version :9

Sequence 1:	NP_001137671.1	Gene:	CG42391 / 7354405	FlyBaseID:	FBgn0259737	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_021329092.1	Gene:	ank1b / 797662	ZFINID:	ZDB-GENE-091113-6	Length:	2091	Species:	Danio rerio

Alignment Length:	214	Identity:	42/214 - (19%)
Similarity:	74/214 - (34%)	Gaps:	66/214 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LQLRNNFKSKVKARPISYSLG-TLH--------------KHHTNFS------TELENTINSESNF 58
            |:|..||....::|.|....| .||              :...:||      ..|..::......
Zfish  1480 LELHENFSEVARSRDIEVMEGMPLHLECSGNLVPVRKATQQPRSFSFQAFRDNRLPVSVKVRDAN 1544

  Fly    59 KNISNLIKFVRQHSKWYRDND------------CI-------NRHYFNYILLDPRVTN------- 97
            |..|..:.|:|:.:| |.|..            |:       .|.....:.|..|.:.
Zfish  1545 KEASGFLSFLRKSTK-YEDTQHVLCNLNITMPPCVKGVGSDDRRRTLTPLALRERYSALSEPGLA 1608

  Fly    98 --NLKER--------ASQLHLMDVWYTFLRAIFYVGKGKATRPYVHLKNAQKLVDETN---NITL 149
              |..||        |.||.|.  |....|.:.: |.....|  :.::|...|:|:::   |:.:
Zfish  1609 AVNAMERTELKITVIAEQLGLS--WTELARELQF-GVDDINR--IRVENPNSLLDQSSALLNLWV 1668

  Fly   150 VKDPKLALIVSIWKANRGV 168
            .::.|.|.:.|::.|.:.:
Zfish  1669 GREGKKAKMESLYGALKNI 1687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42391	NP_001137671.1	Peptidase_S80	<37..>101	CDD:305105	17/111 (15%)
CG42391	NP_001137671.1	GIY-YIG_COG3680_Meta	85..200	CDD:198401	21/104 (20%)
ank1b	XP_021329092.1	ANK repeat	80..108	CDD:293786
		ANK	105..230	CDD:238125
		ANK repeat	110..141	CDD:293786
		ANK repeat	144..174	CDD:293786
		ANK repeat	176..207	CDD:293786
		ANK repeat	209..233	CDD:293786
		ANK repeat	242..269	CDD:293786
		ANK	266..391	CDD:238125
		ANK repeat	272..302	CDD:293786
		ANK repeat	304..335	CDD:293786
		ANK repeat	337..367	CDD:293786
		ANK repeat	370..401	CDD:293786
		Ank_4	371..424	CDD:316185
		ANK repeat	403..433	CDD:293786
		ANK	431..556	CDD:238125
		ANK repeat	436..467	CDD:293786
		ANK repeat	469..500	CDD:293786
		ANK repeat	502..533	CDD:293786
		ANK	530..655	CDD:238125
		ANK repeat	535..563	CDD:293786
		ANK repeat	569..599	CDD:293786
		ANK	600..721	CDD:238125
		ANK repeat	601..632	CDD:293786
		ANK repeat	634..662	CDD:293786
		ANK repeat	667..695	CDD:293786
		ANK	695..820	CDD:238125
		ANK repeat	700..731	CDD:293786
		ANK repeat	733..764	CDD:293786
		ANK repeat	766..797	CDD:293786
		ANK repeat	799..827	CDD:293786
		Ank_4	800..852	CDD:316185
		ZU5	1121..1225	CDD:128514
		Death_ank1	1614..1697	CDD:260067	18/79 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900