DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42391 and 4932414N04Rik

DIOPT Version :9

Sequence 1:	NP_001137671.1	Gene:	CG42391 / 7354405	FlyBaseID:	FBgn0259737	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_006500398.1	Gene:	4932414N04Rik / 75721	MGIID:	1922971	Length:	1106	Species:	Mus musculus

Alignment Length:	269	Identity:	45/269 - (16%)
Similarity:	90/269 - (33%)	Gaps:	103/269 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LRNNFKSKV---KARPISYSLGTLHKHHTNFSTELENTINSESNFKNISNLIKFVRQHSKWYRDN 78
            :||.|..::   ||....|.: |..||     ..|....:||.|     ..:|:.
Mouse   328 VRNGFIQQMHCGKASNHQYPV-TQKKH-----VRLTKKTSSEKN-----KALKYA---------- 371

  Fly    79 DCINRH--------------YFNYILLDPRVTNNLKERASQLHLMDVWYTFLRAIFYVGKGKATR 129
            |.::.|              |.|.:::..::..|.|:....|.:.|..:::        |....|
Mouse   372 DAMDDHQLSESLSEDYDLPDYDNILMIVDQLQMNYKDSGKPLEIQDAVHSY--------KMIVER 428

  Fly   130 PYVHLKNAQKLVDETNNITLVKDPKLALIVSIWKANRGVLLIRAFQGISSQDAQTREASI----- 189
            ...|   ::.|::::.|                |.|:|       ..:..:..:|.:|.:
Mouse   429 NQNH---SELLIEKSKN----------------KRNQG-------HRVMKKPGETEKAKLQLRCR 467

  Fly   190 -----IDALGMNHLTNRRL------GFYYGRARSLSDK------ERKYLGIALLYKLMMKFLAKE 237
                 :|.|.:.....:.:      |:|....:.|::|      |::.|.:.         |..:
Mouse   468 REEQQLDLLDVGSPEKQDMQQRNPDGWYEEMKKELTEKDPQHGREKQQLELR---------LRAQ 523

  Fly   238 EKELFPLKN 246
            :.||..|:|
Mouse   524 DMELQHLRN 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42391	NP_001137671.1	Peptidase_S80	<37..>101	CDD:305105	12/77 (16%)
CG42391	NP_001137671.1	GIY-YIG_COG3680_Meta	85..200	CDD:198401	18/124 (15%)
4932414N04Rik	XP_006500398.1	Smc	<456..>687	CDD:224117	15/86 (17%)
		DUF3496	620..699	CDD:371843
		DUF3496	836..938	CDD:371843
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842151
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930