Protein Alignment CG42391 and Tnks2

DIOPT Version :9

• Sequence 1: NP_001137671.1
• Gene: CG42391 / 7354405
• FlyBaseID: FBgn0259737
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_001157107.1
• Gene: Tnks2 / 74493
• MGIID: 1921743
• Length: 1166
• Species: Mus musculus
• Alignment Length: 235
• Identity: 53/235 - (22%)
• Similarity: 89/235 - (37%)
• Gaps: 56/235 - (23%)

  Fly    26 KARPISYSLGTLHKHHTNFSTELENTINSESNFKNISNLIKFVRQHSKWYRDNDCINRHYFNYIL 90
            |:.|:.::.|...|....:.  |:|..|.::  ::...||..         .|.|...|
Mouse    58 KSTPLHFAAGFGRKDVVEYL--LQNGANVQA--RDDGGLIPL---------HNACSFGH------ 103

  Fly    91 LDPRVTNNLKERASQLHLMDVW-YTFLR--AIFYVGKGKATRPYVHLKN-AQKLVDETNNITL-- 149
              ..|.|.|.:..:..:..|.| ||.|.  ||    |||.....|.|:: |:..:..|:..|.
Mouse   104 --AEVVNLLLQHGADPNARDNWNYTPLHEAAI----KGKIDVCIVLLQHGAEPTIRNTDGRTALD 162

  Fly   150 VKDPKL-ALIVSIWKANRGVLLIRAFQGISSQDAQTREASIIDALGMN-HLTNRR------LGFY 206
            :.||.. |::...:|.:.  ||..|..|     .:.:..:::..|.:| |.::.|      |...
Mouse   163 LADPSAKAVLTGDYKKDE--LLESARSG-----NEEKMMALLTPLNVNCHASDGRKSTPLHLAAG 220

  Fly   207 YGRARSLSDKERKYLGIALLYKLMMKFLAKEEKELFPLKN 246
            |.|.:.          :.||........||::.:|.||.|
Mouse   221 YNRVKI----------VQLLLHHGADVHAKDKGDLVPLHN 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42391	NP_001137671.1	Peptidase_S80	<37..>101	CDD:305105	12/63 (19%)
		GIY-YIG_COG3680_Meta	85..200	CDD:198401	29/122 (24%)
Tnks2	NP_001157107.1	ANK 1	23..52
		Ank_4	28..78	CDD:290365	4/21 (19%)
		ANK	50..164	CDD:238125	30/130 (23%)
		ANK 2	57..86		7/29 (24%)
		ANK repeat	60..88	CDD:293786	6/31 (19%)
		Ank_2	62..154	CDD:289560	26/116 (22%)
		ANK repeat	90..121	CDD:293786	8/47 (17%)
		ANK 3	90..119		8/45 (18%)
		ANK repeat	123..154	CDD:293786	12/34 (35%)
		ANK 4	123..152		12/32 (38%)
		ANK	203..317	CDD:238125	14/58 (24%)
		ANK 5	210..239		6/38 (16%)
		ANK repeat	213..241	CDD:293786	6/37 (16%)
		Ank_2	215..307	CDD:289560	11/46 (24%)
		ANK repeat	243..274	CDD:293786	4/8 (50%)
		ANK 6	243..272		4/8 (50%)
		ANK repeat	276..307	CDD:293786
		ANK 7	276..305
		ANK 8	363..395
		ANK repeat	365..397	CDD:293786
		Ank_2	368..461	CDD:289560
		ANK	394..579	CDD:238125
		ANK repeat	399..430	CDD:293786
		ANK 9	399..428
		ANK 10	432..461
		ANK repeat	433..521	CDD:293786
		Ank_2	437..556	CDD:289560
		ANK 11	463..489
		ANK	518..643	CDD:238125
		ANK 12	525..554
		ANK repeat	528..556	CDD:293786
		Ank_2	530..622	CDD:289560
		HIF1AN-binding. /evidence=ECO:0000250|UniProtKB:Q9H2K2	545..553
		ANK repeat	558..589	CDD:293786
		ANK 13	558..587
		ANK repeat	591..622	CDD:293786
		ANK 14	591..620
		ANK 15	624..652
		ANK repeat	644..674	CDD:293786
		ANK	671..787	CDD:238125
		ANK 16	678..707
		ANK repeat	681..709	CDD:293786
		Ank_2	683..775	CDD:289560
		ANK repeat	711..742	CDD:293786
		ANK 17	711..740
		ANK repeat	744..775	CDD:293786
		ANK 18	744..773
		SAM_tankyrase1,2	871..936	CDD:188923
		SAM	877..933	CDD:197735
		tankyrase_like	938..1160	CDD:238718
		PARP	952..1155	CDD:279038

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900