DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42391 and RNASEL

DIOPT Version :9

Sequence 1:NP_001137671.1 Gene:CG42391 / 7354405 FlyBaseID:FBgn0259737 Length:253 Species:Drosophila melanogaster
Sequence 2:NP_066956.1 Gene:RNASEL / 6041 HGNCID:10050 Length:741 Species:Homo sapiens


Alignment Length:154 Identity:36/154 - (23%)
Similarity:58/154 - (37%) Gaps:43/154 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   115 FLRAIFYVGKGKATR------PYVHLKNAQKLVDETNNITLVKDPKLALIVSIWKANRGVL---- 169
            |:.|..| ||.||.:      ..|:|:...|...|    .|.|....||:.:..|.:..||    
Human   129 FMEAAVY-GKVKALKFLYKRGANVNLRRKTKEDQE----RLRKGGATALMDAAEKGHVEVLKILL 188

  Fly   170 -----------------LIRAFQGISSQDAQTREASIIDALGMNHLTNRRLGFYYGRARSLSDKE 217
                             ||.|.  :||.|:   :...|..|.::|..:..:....|:...:...|
Human   189 DEMGADVNACDNMGRNALIHAL--LSSDDS---DVEAITHLLLDHGADVNVRGERGKTPLILAVE 248

  Fly   218 RKYLGIALLYKLMMKFLAKEEKEL 241
            :|:||      |:.:.|.:|..|:
Human   249 KKHLG------LVQRLLEQEHIEI 266

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42391NP_001137671.1 Peptidase_S80 <37..>101 CDD:305105
GIY-YIG_COG3680_Meta 85..200 CDD:198401 27/111 (24%)
RNASELNP_066956.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21
ANK repeat 24..56 CDD:293786
ANK 1 24..53
Ank_2 29..122 CDD:289560
ANK 2 58..87
ANK 59..188 CDD:238125 18/63 (29%)
ANK repeat 59..89 CDD:293786
ANK repeat 91..122 CDD:293786
ANK 3 91..120
Ank_2 96..199 CDD:289560 18/74 (24%)
ANK repeat 124..154 CDD:293786 8/25 (32%)
ANK 4 124..153 8/24 (33%)
ANK repeat 167..199 CDD:293786 5/31 (16%)
ANK 5 167..197 5/29 (17%)
Ank_2 172..270 CDD:289560 22/106 (21%)
ANK 196..321 CDD:238125 18/82 (22%)
ANK repeat 201..236 CDD:293786 9/39 (23%)
ANK 6 201..234 9/37 (24%)
2-5A binding (P-loop) 1 229..242 1/12 (8%)
ANK 7 238..268 9/35 (26%)
Ank_2 243..326 CDD:289560 8/30 (27%)
2-5A binding (P-loop) 2 253..275 5/20 (25%)
ANK repeat 272..326 CDD:293786
ANK 8 272..301
ANK 9 303..329
PKc_like 375..587 CDD:304357
Pkinase 387..586 CDD:278497
RNase_RNase-L 590..708 CDD:199218
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 715..741
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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