DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42391 and Pidd1

DIOPT Version :9

Sequence 1:	NP_001137671.1	Gene:	CG42391 / 7354405	FlyBaseID:	FBgn0259737	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_073145.1	Gene:	Pidd1 / 57913	MGIID:	1889507	Length:	915	Species:	Mus musculus

Alignment Length:	93	Identity:	23/93 - (24%)
Similarity:	38/93 - (40%)	Gaps:	35/93 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LVFNFIQTIP-----------LQLRNNFKS--------------------KVKARPISY-SLGTL 37
            |.||.::|:|           |.|.:|..|                    :::..|::. ||.||
Mouse   137 LSFNRLETLPTCVPELHGLDALLLSHNHLSELPEALGALPALTFLTVTHNRLERLPLTLGSLSTL 201

  Fly    38 HKHHTNFSTELENTINSE-SNFKNISNL 64
            .:  .:.|..|.:||.|| .|.:::|.|
Mouse   202 QR--LDLSENLLDTIPSEIGNLRSLSEL 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42391	NP_001137671.1	Peptidase_S80	<37..>101	CDD:305105	10/29 (34%)
CG42391	NP_001137671.1	GIY-YIG_COG3680_Meta	85..200	CDD:198401
Pidd1	NP_073145.1	LRR 1	131..152		5/14 (36%)
		LRR_RI	<132..295	CDD:238064	23/93 (25%)
		LRR_8	132..188	CDD:290566	9/50 (18%)
		leucine-rich repeat	132..154	CDD:275380	5/16 (31%)
		LRR 2	154..176		4/21 (19%)
		leucine-rich repeat	155..177	CDD:275380	4/21 (19%)
		LRR_8	176..234	CDD:290566	14/54 (26%)
		LRR 3	177..199		2/21 (10%)
		leucine-rich repeat	178..200	CDD:275380	3/21 (14%)
		LRR 4	200..221		8/22 (36%)
		leucine-rich repeat	201..223	CDD:275380	8/23 (35%)
		LRR_8	222..280	CDD:290566	2/6 (33%)
		LRR 5	223..245		2/5 (40%)
		leucine-rich repeat	224..246	CDD:275380	2/4 (50%)
		LRR 6	246..268
		leucine-rich repeat	247..269	CDD:275380
		LRR 7	269..290
		leucine-rich repeat	270..289	CDD:275380
		ZU5	330..403	CDD:295340
		Peptidase_S68	426..458	CDD:287439
		Peptidase S68. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00485	428..457
		ZU5	469..542	CDD:295340
		Peptidase S68. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00485	571..599
		UPA domain. /evidence=ECO:0000250	585..721
		DD	793..878	CDD:301326
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	888..915
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900