DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42391 and Tnks

DIOPT Version :9

Sequence 1:NP_001137671.1 Gene:CG42391 / 7354405 FlyBaseID:FBgn0259737 Length:253 Species:Drosophila melanogaster
Sequence 2:NP_001262963.1 Gene:Tnks / 43095 FlyBaseID:FBgn0027508 Length:1520 Species:Drosophila melanogaster


Alignment Length:216 Identity:49/216 - (22%)
Similarity:87/216 - (40%) Gaps:55/216 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 IQTIPLQLRNNFKSKVKARPISYSLGTLHKHHTNFSTELENTINSESNFKNISNLIKFVRQH-SK 73
            :.|:...:.||        |||.:...|...|   ||.|    :..:.|..:. :::|:.:| ::
  Fly   497 LDTVRRIVLNN--------PISVNCRDLDGRH---STPL----HFAAGFNRVP-VVQFLLEHGAE 545

  Fly    74 WYR---------DNDCINRHYFNYILLDPRVTNNLKERASQLHLMDVW-YTFLRAIFYVGKGKAT 128
            .|.         .|.|...||        .||..|.:..:.:::.|:| :|.|...  ..|||..
  Fly   546 VYAADKGGLVPLHNACSYGHY--------EVTELLVKHGANVNVSDLWKFTPLHEA--AAKGKYD 600

  Fly   129 RPYVHLKNA-------------QKLVDETNN--ITLVKDPKLALIVSIWKANRG-VLLIRAFQGI 177
            ...:.||:.             ..||.|:::  ..|::.|. ||:.:..|.|.. |..:...:.|
  Fly   601 ICKLLLKHGADPMKKNRDGATPADLVKESDHDVAELLRGPS-ALLDAAKKGNLARVQRLVTPESI 664

  Fly   178 SSQDAQTREASIID-ALGMNH 197
            :.:|||.|.::.:. |.|.|:
  Fly   665 NCRDAQGRNSTPLHLAAGYNN 685

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42391NP_001137671.1 Peptidase_S80 <37..>101 CDD:305105 16/73 (22%)
GIY-YIG_COG3680_Meta 85..200 CDD:198401 31/131 (24%)
TnksNP_001262963.1 ANK 49..163 CDD:238125
ANK repeat 59..87 CDD:293786
Ank_2 61..153 CDD:289560
ANK repeat 89..120 CDD:293786
ANK repeat 122..153 CDD:293786
ANK 202..316 CDD:238125
ANK repeat 212..240 CDD:293786
Ank_2 214..306 CDD:289560
ANK repeat 242..273 CDD:293786
ANK repeat 275..306 CDD:293786
ANK 361..478 CDD:238125
ANK repeat 363..396 CDD:293786
Ank_2 367..459 CDD:289560
ANK 393..573 CDD:238125 21/99 (21%)
ANK repeat 398..429 CDD:293786
ANK repeat 431..459 CDD:293786
ANK repeat 483..515 CDD:293786 6/25 (24%)
Ank_4 486..540 CDD:290365 13/58 (22%)
ANK 512..637 CDD:238125 28/142 (20%)
ANK repeat 522..550 CDD:293786 6/32 (19%)
Ank_2 524..616 CDD:289560 21/106 (20%)
ANK repeat 552..583 CDD:293786 7/38 (18%)
ANK repeat 585..610 CDD:293786 8/26 (31%)
ANK repeat 638..668 CDD:293786 7/30 (23%)
Ank_4 641..693 CDD:290365 13/46 (28%)
ANK 665..779 CDD:238125 7/21 (33%)
ANK repeat 672..703 CDD:293786 4/14 (29%)
Ank_2 677..769 CDD:289560 3/9 (33%)
ANK repeat 705..736 CDD:293786
ANK repeat 738..769 CDD:293786
SAM_tankyrase1,2 887..952 CDD:188923
SAM 890..952 CDD:197735
tankyrase_like 948..1170 CDD:238718
PARP 961..1165 CDD:279038
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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