DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42391 and ankar

DIOPT Version :9

Sequence 1:	NP_001137671.1	Gene:	CG42391 / 7354405	FlyBaseID:	FBgn0259737	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001035135.2	Gene:	ankar / 368636	ZFINID:	ZDB-GENE-030616-533	Length:	1400	Species:	Danio rerio

Alignment Length:	161	Identity:	39/161 - (24%)
Similarity:	65/161 - (40%)	Gaps:	44/161 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 VWYTFLRAIFYVGKGKATRPYVHLKNAQKLVDETNNITLVKDPKLALIVSIWKANRGVLLIRAFQ 175
            ::.|||.:.....|.||....|.|   .:::..::.:||.. ..:.::|.:.::::...:|...|
Zfish  1176 IYETFLNSDNETEKAKAAFQTVVL---ARVISGSDEVTLTA-RGVTILVELLQSDQSTTVIITAQ 1236

  Fly   176 ----------GIS-----------------SQDAQTREASIIDALGMNHLTNRRLGFYYGRARSL 213
                      ||:                 |:|.:.|.| ...|||  :||..|...     |.|
Zfish  1237 LLASLAHMRAGITDAIVSMGATEHLSAHLDSEDEEVRTA-CTSALG--YLTFNRYAH-----RQL 1293

  Fly   214 SDKERKYLGIALLYKLMMKFLAKEEK--ELF 242
            ..|.||...|   |.|:||.||.:.:  :||
Zfish  1294 MTKCRKSPHI---YDLLMKNLAPDARISQLF 1321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42391	NP_001137671.1	Peptidase_S80	<37..>101	CDD:305105
CG42391	NP_001137671.1	GIY-YIG_COG3680_Meta	85..200	CDD:198401	23/115 (20%)
ankar	NP_001035135.2	ANK	489..621	CDD:238125
		Ank_2	489..599	CDD:289560
		ANK repeat	520..550	CDD:293786
		ANK	569..691	CDD:238125
		ANK repeat	569..599	CDD:293786
		Ank_2	574..663	CDD:289560
		ANK repeat	601..630	CDD:293786
		ANK repeat	632..662	CDD:293786
		Ank_4	638..691	CDD:290365
		armadillo repeat	702..726	CDD:293788
		ARM	735..852	CDD:237987
		armadillo repeat	736..768	CDD:293788
		armadillo repeat	784..809	CDD:293788
		ARM	819..937	CDD:237987
		armadillo repeat	826..851	CDD:293788
		armadillo repeat	868..893	CDD:293788
		armadillo repeat	901..937	CDD:293788
		armadillo repeat	943..977	CDD:293788
		ARM	987..1109	CDD:237987
		HEAT repeat	990..1019	CDD:293787
		armadillo repeat	1025..1071	CDD:293788
		armadillo repeat	1077..1108	CDD:293788
		armadillo repeat	1165..1202	CDD:293788	8/28 (29%)
		armadillo repeat	1210..1243	CDD:293788	5/33 (15%)
		ARM	1212..1310	CDD:237987	24/109 (22%)
		armadillo repeat	1249..1283	CDD:293788	7/36 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900