Protein Alignment CG42391 and ANKRD62

DIOPT Version :10

• Sequence 1: NP_001137671.1
• Gene: CG42391 / 7354405
• FlyBaseID: FBgn0259737
• Length: 253
• Species: Drosophila melanogaster
• Sequence 2: NP_001264262.1
• Gene: ANKRD62 / 342850
• HGNCID: 35241
• Length: 917
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 53/264 - (20%)
• Similarity: 101/264 - (38%)
• Gaps: 46/264 - (17%)

  Fly    22 KSKVKARPISYSLGTLHKH-HTNFST-ELENTINSESNF--KNISNL------IKFVRQ--HSKW 74
            :||:..:.:...|.|:..: :.||.| |.|..:..|::.  ..|:.|      ||...|  .:|:
Human   525 QSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKY 589

  Fly    75 YRDNDCI--NRHYFNYILL--DPRVTNNLKERASQLHLMDVWYTFLRAIFYVGKGKATRPYVHLK 135
            ::|.:.|  |.......|.  :..:|..:...:.:|:::....|.|.:.....|...:|....::
Human   590 FKDIEIIKENNEDLEKTLKRNEEALTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETEME 654

  Fly   136 N-----AQKLVDETNNITLVKDPKLAL--IVSIW-----KANRGVLLI--------RAFQGISSQ 180
            :     |..|.|.....:..:|.:||.  .|:.|     ..|..:.::        ....|:.::
Human   655 SYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAESTSSGLETE 719

  Fly   181 DAQTREASIIDALGMNHLTNRRLGFYYGRARSLSDKERKYLGIALLYKLMMKFLAKE---EKELF 242
            ....|||.....|.:.|:.    |......|.|.|.|..|...   ..::.|::.|:   |..||
Human   720 LHYEREALKEKTLHIEHMQ----GVLSRTQRRLEDIEHMYQND---QPILEKYVRKQQSVEDGLF 777

  Fly   243 PLKN 246
            .|::
Human   778 QLQS 781

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42391	NP_001137671.1	GIY-YIG_COG3680_Meta	85..200	CDD:198401	22/136 (16%)
ANKRD62	NP_001264262.1	ANKYR	37..263	CDD:440430
		ANK repeat	42..69	CDD:293786
		ANK 1	71..100
		ANK repeat	73..102	CDD:293786
		ANK repeat	104..135	CDD:293786
		ANK 2	104..133
		ANK repeat	137..167	CDD:293786
		ANK 3	137..166
		ANK repeat	170..201	CDD:293786
		ANK 4	170..199
		ANK repeat	203..234	CDD:293786
		ANK 5	203..232
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	265..367
		SCP-1	<268..893	CDD:114219	53/264 (20%)
		CCDC144C	561..846	CDD:464371	43/228 (19%)