DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42391 and Tnks

DIOPT Version :9

Sequence 1:	NP_001137671.1	Gene:	CG42391 / 7354405	FlyBaseID:	FBgn0259737	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001099554.2	Gene:	Tnks / 290794	RGDID:	1308784	Length:	1317	Species:	Rattus norvegicus

Alignment Length:	142	Identity:	35/142 - (24%)
Similarity:	53/142 - (37%)	Gaps:	35/142 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 NDCINRHYFNYILLDPRVTNNLKERASQLHLMDVW-YTFLRAIFYVGKGKATRPYVHLKN----A 137
            |.|...||        .|...|....:.:::.|:| :|.|...  ..|||.....:.||:    .
  Rat   713 NACSYGHY--------EVAELLVRHGASVNVADLWKFTPLHEA--AAKGKYEICKLLLKHGADPT 767

  Fly   138 QKLVDETNNITLVKDPKLALIVSIWKANRG--VLLIRAFQG-------------ISSQDAQTREA 187
            :|..|....:.|||:..    ..|....||  .||..|.:|             |:.:|.|.|.:
  Rat   768 KKNRDGNTPLDLVKEGD----TDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNS 828

  Fly   188 SIID-ALGMNHL 198
            :.:. |.|.|:|
  Rat   829 TPLHLAAGYNNL 840

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42391	NP_001137671.1	Peptidase_S80	<37..>101	CDD:305105	6/22 (27%)
CG42391	NP_001137671.1	GIY-YIG_COG3680_Meta	85..200	CDD:198401	32/135 (24%)
Tnks	NP_001099554.2	ANK	198..312	CDD:238125
		ANK repeat	208..236	CDD:293786
		Ank_2	210..302	CDD:289560
		ANK repeat	238..269	CDD:293786
		ANK	266..445	CDD:238125
		ANK repeat	271..302	CDD:293786
		Ank_4	329..379	CDD:290365
		ANK repeat	361..389	CDD:293786
		Ank_2	363..455	CDD:289560
		ANK repeat	391..422	CDD:293786
		ANK repeat	424..455	CDD:293786
		ANK	513..629	CDD:238125
		ANK repeat	513..545	CDD:293786
		Ank_2	516..609	CDD:289560
		ANK repeat	547..578	CDD:293786
		ANK repeat	580..609	CDD:293786
		Ank_2	585..704	CDD:289560
		ANK	666..791	CDD:238125	21/91 (23%)
		ANK repeat	676..704	CDD:293786
		Ank_2	678..770	CDD:289560	15/66 (23%)
		ANK repeat	706..737	CDD:293786	6/31 (19%)
		ANK repeat	739..770	CDD:293786	8/32 (25%)
		Ank_4	793..847	CDD:290365	13/48 (27%)
		ANK	819..943	CDD:238125	7/22 (32%)
		ANK repeat	826..857	CDD:293786	5/15 (33%)
		Ank_2	831..923	CDD:289560	4/10 (40%)
		ANK repeat	859..890	CDD:293786
		ANK repeat	892..923	CDD:293786
		SAM_tankyrase1,2	1014..1079	CDD:188923
		SAM	1020..1077	CDD:197735
		tankyrase_like	1081..1303	CDD:238718
		PARP	1095..1298	CDD:279038
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900