DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42391 and ANK2

DIOPT Version :9

Sequence 1:NP_001137671.1 Gene:CG42391 / 7354405 FlyBaseID:FBgn0259737 Length:253 Species:Drosophila melanogaster
Sequence 2:NP_001373103.1 Gene:ANK2 / 287 HGNCID:493 Length:4183 Species:Homo sapiens


Alignment Length:168 Identity:34/168 - (20%)
Similarity:64/168 - (38%) Gaps:45/168 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 KARPISYSLGTLHKH---HTNFSTELENTINSESNFKNISNLIKFVRQHSKWYRDNDCINRH--- 84
            |.:|:| :.|...||   ..:..||.:..::..|..:.|...:. ||:..|.::.....::|   
Human  1994 KHQPVS-TAGKTEKHLPVSPSGKTEKQPPVSPTSKTERIEETMS-VRELMKAFQSGQDPSKHKTG 2056

  Fly    85 YFNYILLDPRVTNNLKERASQLHLMDVWYTFLRAIFYVGKGKA-----TRPYVHLKNAQKLVDET 144
            .|.:        .:.|::..|                 .|||.     ..|.:..:.|||    |
Human  2057 LFEH--------KSAKQKQPQ-----------------EKGKVRVEKEKGPILTQREAQK----T 2092

  Fly   145 NNITLVKDPKLALIVSIWKANRGVLLIRAFQGISSQDA 182
            .|.|:.:..:|. :....::.|||.:  :..|:..:||
Human  2093 ENQTIKRGQRLP-VTGTAESKRGVRV--SSIGVKKEDA 2127

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42391NP_001137671.1 Peptidase_S80 <37..>101 CDD:305105 11/69 (16%)
GIY-YIG_COG3680_Meta 85..200 CDD:198401 20/103 (19%)
ANK2NP_001373103.1 Ank_2 35..>311 CDD:423045
ANK repeat 80..111 CDD:293786
ANK repeat 113..144 CDD:293786
ANK repeat 146..171 CDD:293786
Ank_2 202..>444 CDD:423045
ANK repeat 212..247 CDD:293786
ANK repeat 249..280 CDD:293786
ANK repeat 282..313 CDD:293786
ANK repeat 315..345 CDD:293786
ANK repeat 348..379 CDD:293786
ANK repeat 381..411 CDD:293786
ANK repeat 414..445 CDD:293786
PHA03095 421..>706 CDD:222980
ANK repeat 447..478 CDD:293786
ANK repeat 480..511 CDD:293786
ANK repeat 513..542 CDD:293786
ANK repeat 546..571 CDD:293786
Ank_2 578..>802 CDD:423045
ANK repeat 579..604 CDD:293786
ANK repeat 612..643 CDD:293786
ANK repeat 645..676 CDD:293786
ANK repeat 678..707 CDD:293786
ANK repeat 711..742 CDD:293786
ANK repeat 744..775 CDD:293786
ANK repeat 777..806 CDD:293786
Ank_4 778..830 CDD:372654
ZU5 1013..1150 CDD:128514
UPA_2 1371..1500 CDD:375346
PspC_subgroup_1 1549..>1922 CDD:411407
PTZ00449 <1717..2161 CDD:185628 34/168 (20%)
Streccoc_I_II <1843..>2027 CDD:411384 8/33 (24%)
Spc7_N <2493..>2634 CDD:373822
rad2 <3031..>3565 CDD:273166
PRK14949 <3196..>3442 CDD:237863
Death_ank2 3614..3697 CDD:260066
NESP55 <3770..>3884 CDD:115071
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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