DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42391 and F36D3.5

DIOPT Version :9

Sequence 1:	NP_001137671.1	Gene:	CG42391 / 7354405	FlyBaseID:	FBgn0259737	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_507181.3	Gene:	F36D3.5 / 185352	WormBaseID:	WBGene00009471	Length:	1215	Species:	Caenorhabditis elegans

Alignment Length:	250	Identity:	48/250 - (19%)
Similarity:	89/250 - (35%)	Gaps:	51/250 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 IQTIPLQLRNNFKSKVKARPISYSLGTLHKHHTNFSTELENTINSESNFKNI----SNLIKFVRQ 70
            ||...:.:.|..|..:.||....|.......:..:....||.:|..:|.|:|    :..:.|:..
Worm   402 IQDSRIHINNCMKETLLARSKLKSFDASIVEYEKYMFPAENIMNRLANIKDIIAELTVALNFMVY 466

  Fly    71 HSKWYRD---NDCINRHYFNYILLDPRVTNNLKERASQLH----LMDVWYTFLRAIFYVGKGKAT 128
            .:...||   :|| :..|:....||...:|.:..:...:.    |....|:|:..:..:.|
Worm   467 PNTQARDLFKDDC-HTLYWTLSKLDVNTSNAITVKNMLIRDFKKLTHHSYSFIDTMKSIAK---- 526

  Fly   129 RPYVHLKNAQKLVDETNNITLVKD-PKLALIVSIWKANRGVLLIRAFQGISSQDAQTREASII-- 190
                 :.:..|:|::|:......| |.|..:||      .:.|::..|..|......:|..:|
Worm   527 -----ISSELKIVEKTSAGIYDSDGPNLGDLVS------ELELVKTSQCFSHHSETIQELMLIVH 580

  Fly   191 ----DALGMNHLTNRRLGFYYGRARSLSDKERKYLGIALLYKLMMKFLAKEEKEL 241
                .....:|.|:..:..|..|...:.:.                 ||..|||:
Worm   581 KLYSTRYPPDHATSSTMHEYLDRLEKVQNN-----------------LALVEKEI 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42391	NP_001137671.1	Peptidase_S80	<37..>101	CDD:305105	15/70 (21%)
CG42391	NP_001137671.1	GIY-YIG_COG3680_Meta	85..200	CDD:198401	22/125 (18%)
F36D3.5	NP_507181.3	WSN	25..93	CDD:197734
		ANK	<873..946	CDD:238125
		ANK repeat	876..907	CDD:293786
		Ank_4	879..930	CDD:290365
		ANK repeat	909..940	CDD:293786
		BRCT	985..1065	CDD:214602
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900