DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42391 and C18H2.5

DIOPT Version :9

Sequence 1:	NP_001137671.1	Gene:	CG42391 / 7354405	FlyBaseID:	FBgn0259737	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_741231.2	Gene:	C18H2.5 / 176082	WormBaseID:	WBGene00015992	Length:	1195	Species:	Caenorhabditis elegans

Alignment Length:	214	Identity:	50/214 - (23%)
Similarity:	88/214 - (41%)	Gaps:	45/214 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 STELENTINSESNFKNISNLIKFVRQHSKWYRDN-------------DCINRHYFNYILLDPRVT 96
            |.:.|:....:.:.|.:|:|...:.:...|..:.             |.:|.  .|...|:|:.|
Worm   411 SAQTEDFARFDEHSKTLSDLNSTIFEVLAWCNETVKQNDFDVMETALDSLNN--LNLENLNPQET 473

  Fly    97 -NNLKERASQLHLMDVWYTFLRAIFYVGKGKATRPY--VHLKNAQKLVDET-NNITLVKDPKLAL 157
             |.::|..:...|.|.:..|||  |::.:.|....|  :|..|...:::|| .|:|..|
Worm   474 INEVREIQNFEDLNDFFERFLR--FHLLQKKYDTDYQLLHKVNLVDVMEETAANLTKSK------ 530

  Fly   158 IVSIWKANRGVLLIRAFQGISSQDAQTREASIIDALGMNHLTN-RRLGFYYGRARSLSDKERKYL 221
              ||  ||...|.::.||  ||:...|.|          .:|: ||:| .....:.:.|..:.|.
Worm   531 --SI--ANLKCLKMKEFQ--SSKIHSTVE----------FITSVRRIG-NSSDHKKIKDAVKIYS 578

  Fly   222 GIALLYKLMMKFLAKEEKE 240
            .:...|..:.|||.:..::
Worm   579 DMRTDYVAVEKFLEETRRQ 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42391	NP_001137671.1	Peptidase_S80	<37..>101	CDD:305105	13/69 (19%)
CG42391	NP_001137671.1	GIY-YIG_COG3680_Meta	85..200	CDD:198401	32/118 (27%)
C18H2.5	NP_741231.2	WSN	40..108	CDD:197734
		Ank_4	856..909	CDD:290365
		ANK	860..>924	CDD:238125
		ANK repeat	860..886	CDD:293786
		ANK repeat	888..922	CDD:293786
		BRCT	964..1044	CDD:214602
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900