DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42391 and ANKRD61

DIOPT Version :9

Sequence 1:	NP_001137671.1	Gene:	CG42391 / 7354405	FlyBaseID:	FBgn0259737	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	NP_001258629.1	Gene:	ANKRD61 / 100310846	HGNCID:	22467	Length:	418	Species:	Homo sapiens

Alignment Length:	137	Identity:	39/137 - (28%)
Similarity:	53/137 - (38%)	Gaps:	43/137 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 NAQKLVDETNNITLVKDPKLALIVSIWKANR----GVLLIRAF----QGISSQD--AQT------ 184
            |....|..|.|..|    |||:..:..||.|    ||..||..    ..:::||  .||
Human   226 NVNCAVSSTGNTPL----KLAVCTASSKAGRLLGAGVSCIRLLLTHGAKVNAQDYKGQTAIHEAC 286

  Fly   185 ---REASIIDAL-----GMNHLT-NRRLGFYYGRARSLSDKERKYLGIALLYKLMMKFLAKEEKE 240
               ||| ||:.|     .:|.|| |.....|....||.:.::     .|||.:|:.        .
Human   287 FGGREA-IINLLLEFEANVNILTRNGESPIYMYLQRSCNVRD-----TALLARLLY--------H 337

  Fly   241 LFPLKNT 247
            .:||:.|
Human   338 TYPLRMT 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42391	NP_001137671.1	Peptidase_S80	<37..>101	CDD:305105
CG42391	NP_001137671.1	GIY-YIG_COG3680_Meta	85..200	CDD:198401	28/88 (32%)
ANKRD61	NP_001258629.1	ANK 1	27..57
		ANK	<32..115	CDD:295348
		ANK 2	75..104
		ANK	79..221	CDD:238125
		ANK repeat	79..106	CDD:293786
		Ank_2	80..198	CDD:289560
		ANK repeat	108..163	CDD:293786
		ANK 3	132..161
		ANK	166..298	CDD:238125	24/76 (32%)
		ANK 4	167..196
		ANK repeat	169..198	CDD:293786
		Ank_2	172..275	CDD:289560	15/52 (29%)
		ANK repeat	200..232	CDD:293786	1/5 (20%)
		ANK 5	200..229		1/2 (50%)
		ANK repeat	234..275	CDD:293786	13/44 (30%)
		ANK 6	234..273		13/42 (31%)
		Ank_5	263..317	CDD:290568	14/54 (26%)
		ANK	272..>351	CDD:238125	24/87 (28%)
		ANK repeat	277..308	CDD:293786	9/31 (29%)
		ANK 7	277..306		8/29 (28%)
		ANK 8	310..343		10/45 (22%)
		ANK repeat	319..345	CDD:293786	9/39 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4177
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900