Protein Alignment Ir60d and Ir67c

DIOPT Version :10

• Sequence 1: NP_001137757.2
• Gene: Ir60d / 7354402
• FlyBaseID: FBgn0259187
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_729609.1
• Gene: Ir67c / 317838
• FlyBaseID: FBgn0052058
• Length: 573
• Species: Drosophila melanogaster
• Alignment Length: 626
• Identity: 140/626 - (22%)
• Similarity: 247/626 - (39%)
• Gaps: 147/626 - (23%)

  Fly    31 LHYKTILLVGGSSTCWSLE-----------------------PFETGVPILNLRGENNAYPQ--- 69
            |.:..|:|:...|..||..                       ..:.|..:.||...:.|...
  Fly     5 LIFLNIILLSDRSESWSAREVIHQFNHDQQLQLNIYLDCNDVELQIGQEVSNLFVNSTADKMKIL 69

  Fly    70 DTFNSQMLALACLQTESEDAVKLLYRSLKDMRD-------TPTLLFASSEEHIHDTLFLGCFREN 127
            ..|:|..|.:||.:..:.:      |:|..:::       .|.|....|.   .|..|....|..
  Fly    70 GRFSSHSLIIACFKDSTRN------RTLNGVKELLWGLQYLPILFVVDSN---MDFYFQQALRHG 125

  Fly   128 MLNVLALTASSKEFIYSYQAFPTFRVIKRKLVEIHR-------YFEPQLKDLGGHIVSALPGNIM 185
            .::||||...:.. :|:|:.:|.        ||:|:       |...:|::|.|..|......:.
  Fly   126 FIHVLALNFMNGS-LYTYKPYPK--------VEVHQIKDMQKFYKLTKLRNLQGQAVRTTVETMT 181

  Fly   186 PRTMCYRNAEGERQLAGYLNTFIRNYVESINGTLRISWG---LVPEDD----MRHLTISRLSKIQ 243
            ||...|||..|:...|||:...::.::.:.|||....:|   .||..:    :::..|..:.:|.
  Fly   182 PRCFRYRNRHGQLVYAGYMYRMVKEFISTYNGTEEHVFGNVDTVPYKEGLAALKNGEIDMMPRII 246

  Fly   244 HVDFPLGIIPLYNKTDKQHVYMEISSWFLMLPMETSVPRAHLFVKLGLERLLPIIVVVGAVLGNA 308
            |.   |.....|    :.|:...|.: ::|:|....:|::..|:: .....:.|.::|..|..:
  Fly   247 HA---LEWYYFY----RSHILYNIKT-YIMVPWAEPLPKSLYFIQ-PFRGTVWITIMVSFVYAS- 301

  Fly   309 HRIEVGLGPSWRCYYLADKVLRGALAQPIV--------LPR------RLSPKLMLIYSLLLLSGF 359
              |.:     |...|....  ..:|.|..:        ||.      .:....::.:.:|.:.||
  Fly   302 --IVI-----WWIRYRQQG--NSSLTQSFMDVLQLLFQLPLSKIWHFNMGTHQVVSFIVLFVFGF 357

  Fly   360 FLSNYYMASLTTWLVHPPASDRILEWDQL--------------RYLH--LKVLTIPEEFKYMSLI 408
            .|:|.|.|.|:::|.......:|..:|.|              ..||  .|...|.:||:
  Fly   358 MLTNLYTAQLSSYLTTGLFKSQINTFDDLFREKRTLLVESFDAEVLHNMTKEKIIQKEFE----- 417

  Fly   409 LGTDFMTAYGSIFQLTNSTDFQRRRISMDPSYAYPVTTSLWPFLELSQVR-LRRPLF---RRSYD 469
                      ||..:|:..:..:.|.|::.||||........| ||||.| ||.|:|   :..||
  Fly   418 ----------SIILITSIEEVFKHRKSLNTSYAYEAYEDRIAF-ELSQQRYLRVPIFKILKEVYD 471

  Fly   470 MVLQP-FQVMSLPLPRNSIFHKSLLRYAALTRETGLYYYWFRRSYYELVALGKISYKEEEGNPYC 533
            .  :| |..:...||...:|:..|.|..    |:|::......|:.|.:|.|:||:::.:..
  Fly   472 Q--RPVFVALRHGLPYVELFNNYLRRIF----ESGIWIKLQEDSFLEGIASGEISFRKSKSR--- 527

  Fly   534 DLKWNDFRIVWLAF--LG-GTIISCLALLLEVAHYRWHLGN 571
            ::|..|....:.|:  || |..:|.:||.||:..:::.:.|
  Fly   528 EIKIFDKDFYFFAYILLGMGWCVSTIALFLELWSFKYSVTN 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60d	NP_001137757.2	None
Ir67c	NP_729609.1	7tm_GPCRs	<279..357	CDD:475119	12/88 (14%)
		TM helix 5	279..306	CDD:320097	5/35 (14%)