Protein Alignment Ir60b and Ir40a

DIOPT Version :10

• Sequence 1: NP_001137755.1
• Gene: Ir60b / 7354400
• FlyBaseID: FBgn0259185
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Alignment Length: 600
• Identity: 121/600 - (20%)
• Similarity: 192/600 - (32%)
• Gaps: 226/600 - (37%)

  Fly     5 LYLIIAIGLVDVHCVSLRYILNALE--------NELQYRAILLVESASEIESCWEQKYIQGAVPI 61
            ::..:|:||       |.|:|..|.        |:....||.|.:....::        |.::.|
  Fly     1 MHKFLALGL-------LPYLLGLLNSTRLTFIGNDESDTAIALTQIVRGLQ--------QSSLAI 50

  Fly    62 LNFNANQSLYLKDALNTNILALVCLNEN---VESTMQALY-ENLEDMRDTPTILFVLSDSKVQDV 122
            |   |..||.|.|.        ||..|.   ::..:|.|: .|.:.:..:.|.||.....:....
  Fly    51 L---ALPSLALSDG--------VCQKERNVYLDDFLQRLHRSNYKSVVFSQTELFFQHIEENLQG 104

  Fly   123 FLECLR------RKMLNVLAFKGLDRG-----FVYSFRAFPTFRVIERNVMDILQYFEQQLEDLG 176
            ..||:.      .::||.|..:.|...     |.:..|..|:.|||.         |.:.|
  Fly   105 ANECISLILDEPNQLLNSLHDRHLGHRLSLFIFYWGARWPPSSRVIR---------FREPL---- 156

  Fly   177 GHTLTTLPDNIIPRTVVYKSPDGSRQLAGYLYPFLRNYVSTINATLKVCWHLVPEDGMIQL---- 237
                         |.||...|   |:.|..:|         .|.. :.|     .|..:||
  Fly   157 -------------RVVVVTRP---RKKAFRIY---------YNQA-RPC-----SDSQLQLVNWY 190

  Fly   238 -GEVVRLSEIHDVDFPLGMHGIEHGSTSQNVPLEVSSWFLMLPMEPSLSRAQFFIML-GFEK--- 297
             |:.:.|..|..:...|.::....|.|.:........||.:.....|....:.|..| ..||
  Fly   191 DGDNLGLQRIPLLPTALSVYANFKGRTFRVPVFHSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKV 255

  Fly   298 -VT-----PVLLLLTILLS-------------TAHRIEMGLRPSWRCYVLGDRVLQGTLGQA-FF 342
             ||     .:|:||:..::             .:.|.|.| :.|...:..|..:||.  ||| ||
  Fly   256 RVTGGRDHRLLMLLSKHMNFRFKYIEAPGRTQGSMRSEDG-KDSNDSFTGGIGLLQS--GQADFF 317

  Fly   343 L-------PRRLSVKLMLVYSLILLNGFTFSNYSITSLETWLVHPPSGHPIHSWEQMRTLNLKVL 400
            |       .||.:::              ||.:::.....:..|.|           |.||..:.
  Fly   318 LGDVGLSWERRKAIE--------------FSFFTLADSGAFATHAP-----------RRLNEALA 357

  Fly   401 IV-PSELDSMTKAL------GKQF------------TESNSDLFELSKSGNFQDKRLAMDQSYAY 446
            |: |.:.|.....:      |..|            ..:|||:..|.:        |.:..:|..
  Fly   358 IMRPFKQDIWPHLILTIIFSGPIFYGIIALPYIWRRRWANSDVEHLGE--------LYIHMTYLK 414

  Fly   447 PVTCTLWPLLEHAQIRLPKPEFRRSREMVLIPLLIMAMPLPKNSMFHKSLNRYRALTHQSGLYEF 511
            .:|..|..|         ||.           .::.|..:| :.:|.|.:
  Fly   415 EITPRLLKL---------KPR-----------TVLSAHQMP-HQLFQKCI--------------- 443

  Fly   512 WF------KRSFNEL 520
            ||      |:|.|||
  Fly   444 WFTLRLFLKQSCNEL 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir60b	NP_001137755.1	None
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	20/87 (23%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	24/120 (20%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866