DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17454 and Smn

DIOPT Version :9

Sequence 1:	NP_001138001.1	Gene:	CG17454 / 7354399	FlyBaseID:	FBgn0039977	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_001261954.1	Gene:	Smn / 39844	FlyBaseID:	FBgn0036641	Length:	226	Species:	Drosophila melanogaster

Alignment Length:	165	Identity:	35/165 - (21%)
Similarity:	59/165 - (35%)	Gaps:	38/165 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 DEVITLTRDLIQTQLEEQNKSSYVEPSSTKRDSSNYFDEIEAALLEAEKLVSAAKI--------- 91
            ||.:.|.|:.:..:|               .||:|..:|..||..|.|    |.:|
  Fly    20 DESVGLAREALARRL---------------ADSTNKREEENAAAAEEE----AGEISATGGATSP 65

  Fly    92 ----WKKGDKCQAKWKEDRQYYDATIEDISSTGEVNVIFDAYQNRSTTHVNELRE---RTIRNEV 149
                :|.||..:|.:.:...|..|.:......|...:.:..|:|.....:.:|..   :.:|.|.
  Fly    66 EPVSFKVGDYARATYVDGVDYEGAVVSINEEKGTCVLRYLGYENEQEVLLVDLLPSWGKRVRREQ 130

  Fly   150 FPSNKRHRPNQKEYLKKRKQKKQQRFKDLEEERES 184
            |...|:   ::.|.|.:.|.......|..:..|.|
  Fly   131 FLIAKK---DEDEQLSRPKASAGSHSKTPKSSRRS 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17454	NP_001138001.1	TroA-like	<22..>116	CDD:294188	21/92 (23%)
CG17454	NP_001138001.1	TUDOR	95..142	CDD:119391	9/46 (20%)
Smn	NP_001261954.1	SMN	2..215	CDD:283622	35/165 (21%)
Smn	NP_001261954.1	TUDOR	68..122	CDD:295375	10/53 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458101
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D539238at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR13681
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.040