DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17454 and smr-1

DIOPT Version :9

Sequence 1:	NP_001138001.1	Gene:	CG17454 / 7354399	FlyBaseID:	FBgn0039977	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_001022932.1	Gene:	smr-1 / 175281	WormBaseID:	WBGene00004891	Length:	239	Species:	Caenorhabditis elegans

Alignment Length:	254	Identity:	72/254 - (28%)
Similarity:	115/254 - (45%)	Gaps:	56/254 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADDLHNYKLQLQQVEAALQTDPENEELLKLRSDLDEVITLTRDLIQTQLEEQNKSSYVEPSSTK 65
            |.::|.:||||||||||||..||.|.|||||:.||.|:|:|..||.:|...|.::.:.|.|....
Worm     1 MEEELASYKLQLQQVEAALLGDPTNVELLKLKEDLGEIISLQEDLAETDKAESSERAVVAPQVIH 65

  Fly    66 RDSSNYFDEIEAALLEAEKLVSAAKIWKKGDKCQAKWKEDRQYYDATIEDISSTGEVNVIFDAYQ 130
            :                         |..|::..|...:.::.: |.|:.::..| |.:.|.:..
Worm    66 K-------------------------WTVGERVIAPHPDGKKVF-ARIDSLTPAG-VAITFTSTG 103

  Fly   131 NRSTTHVNELR---ERTIRNEVF--------PS---NKRHRPNQKEYLKKRKQKKQQRFKDLEEE 181
            .::.....:|:   |...:|..|        ||   .|:....:||..:::..||||:.|:|:..
Worm   104 TKTIVDPADLQLPPENQRKNYAFDNTKSAAGPSTQHGKKEWQAEKERRRQKALKKQQKQKELDSI 168

  Fly   182 RESDKNKWLNFNNKNQKK--NGMKARSIFASPDNVSGRVGVGTCGTAGKGMTDFTVGEK 238
            ::.:|..|..||.|...|  .|:|..|...|..:       |:..::|.|      |||
Worm   169 KDGEKKSWQKFNTKANAKGLKGLKKVSATGSSQD-------GSASSSGGG------GEK 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17454	NP_001138001.1	TroA-like	<22..>116	CDD:294188	24/93 (26%)
CG17454	NP_001138001.1	TUDOR	95..142	CDD:119391	8/49 (16%)
smr-1	NP_001022932.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162790
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I3774
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54699
OrthoDB	1	1.010	-	-		D1459016at2759
OrthoFinder	1	1.000	-	-		FOG0005574
OrthoInspector	1	1.000	-	-		oto18671
orthoMCL	1	0.900	-	-		OOG6_103070
Panther	1	1.100	-	-	LDO	PTHR13681
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3989
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.910