DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-22C and acanb

DIOPT Version :9

Sequence 1:	NP_001137766.1	Gene:	lectin-22C / 7354375	FlyBaseID:	FBgn0259230	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_021326217.1	Gene:	acanb / 559593	ZFINID:	ZDB-GENE-100422-16	Length:	1376	Species:	Danio rerio

Alignment Length:	253	Identity:	54/253 - (21%)
Similarity:	100/253 - (39%)	Gaps:	68/253 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 SQNLANSNNSSKANEVLVRQ-----YTMEG----QLTALQNKQLSIEVALDAQGRKLNVNEQNFT 110
            |.:::|| .|.::|::|..:     .|||.    ..:.|.....:|.|........|.:.:....
Zfish  1052 SISVSNS-TSHESNDLLPERDEKISVTMEAFDVTDKSPLITTPTNIPVLTTPSSASLQMPKSTMN 1115

  Fly   111 ERLN-----------CMEGILSALEKTVLEVKTKIKYLG--------------FEQIGSKYYYIE 150
            ..:|           |.:|:.| |:..|...:....:.|              .|.:||.|.:.:
Zfish  1116 PSVNEAPSDPCDPNPCGQGLCS-LQDGVALCQCHSGFSGENCSVLVQGCAEGWMEFMGSCYIHFD 1179

  Fly   151 KVSEKNWSTASKTCRNMGGHLADIKDEADLAAIKANLKEDTHYWLGINDLDHEGKFLSMPTGKQT 215
            :  .:.|::|.:.|:.:..||..|..:.:...:|...::  :.|:|:||.|.:.:|
Zfish  1180 E--RETWTSAEQHCQELNSHLVSISSQQEQEFVKTQAQD--YQWIGLNDKDVQNEF--------- 1231

  Fly   216 TFLKWASG--------RPSQLDTL-----NCVFLY---NGEMYDYPCHYTFRFICQTE 257
               :|..|        ||:|.|..     :||.:.   ||:..|.||:|...|.|::|
Zfish  1232 ---RWTDGSPLEYENWRPNQPDNYFSTGEDCVVMIWHENGQWNDVPCNYHLPFTCKSE 1286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-22C	NP_001137766.1	CLECT	146..255	CDD:153057	29/124 (23%)
acanb	XP_021326217.1	Ig	45..159	CDD:325142
		Link_domain_CSPGs_modules_1_3	158..252	CDD:239594
		Link_domain_CSPGs_modules_2_4	260..354	CDD:239597
		Xlink	459..553	CDD:306661
		Link_domain_CSPGs_modules_2_4	560..655	CDD:239597
		CLECT	1163..1284	CDD:321932	32/136 (24%)
		CCP	1290..1347	CDD:153056
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4956
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940