Protein Alignment lectin-22C and ASGR2

DIOPT Version :10

• Sequence 1: NP_001137766.1
• Gene: lectin-22C / 7354375
• FlyBaseID: FBgn0259230
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: XP_011522164.2
• Gene: ASGR2 / 433
• HGNCID: 743
• Length: 410
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 56/282 - (19%)
• Similarity: 95/282 - (33%)
• Gaps: 76/282 - (26%)

  Fly    33 PPSQ------CGGFCLGVLTPVLNHL-------TISQNLANSNNSSKANEVLVRQYTMEGQLTAL 84
            ||:|      |...|..:|....|.|       |.||:..:......|     |...::.:|.:|
Human   136 PPAQPLAQRLCSMVCFSLLALSFNILLLVVICVTGSQSEGHGGQQGWA-----RGAQLQAELRSL 195

  Fly    85 Q-------------------------NKQLSIEVALDAQGRKLNVNEQNFTERLN---------- 114
            :                         :|..|:...|:.|.:.|..:.......|.
Human   196 KEAFSNFSSSTLTEVQAISTHGGSVGDKITSLGAKLEKQQQDLKADHDALLFHLKHFPVDLRFVA 260

  Fly   115 CMEGIL--SALEKTVLEVKTKIKYLGFEQIGSKYYYIEKVSEKNWSTASKTCRNMGGHLADIK-- 175
            |...:|  :..::|...|.      ..|..||.|::..  |.|.|:.|.|.|:....||..|.
Human   261 CQMELLHSNGSQRTCCPVN------WVEHQGSCYWFSH--SGKAWAEAEKYCQLENAHLVVINSW 317

  Fly   176 DEADLAAIKANLKEDTHYWLGINDLDHEGKFLSMPTGKQTTFLKWASGRPSQL------DTLNCV 234
            :|........|   ..:.|:|:.|.|...|::. .|..:..:..||..:|...      .:.:||
Human   318 EEQKFIVQHTN---PFNTWIGLTDSDGSWKWVD-GTDYRHNYKNWAVTQPDNWHGHELGGSEDCV 378

  Fly   235 FLY-NGEMYDYPCHYTFRFICQ 255
            .:. :|...|..|...:|::|:
Human   379 EVQPDGRWNDDFCLQVYRWVCE 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lectin-22C	NP_001137766.1	CLECT	146..255	CDD:153057	27/117 (23%)
ASGR2	XP_011522164.2	Lectin_N	96..266	CDD:461106	22/134 (16%)
		CLECT_DC-SIGN_like	276..401	CDD:153060	32/137 (23%)