Protein Alignment lectin-22C and ASGR1

DIOPT Version :10

• Sequence 1: NP_001137766.1
• Gene: lectin-22C / 7354375
• FlyBaseID: FBgn0259230
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_001662.1
• Gene: ASGR1 / 432
• HGNCID: 742
• Length: 291
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 63/267 - (23%)
• Similarity: 106/267 - (39%)
• Gaps: 39/267 - (14%)

  Fly     9 LCG---LLALNLYGAWAESDVICPLKDPPSQCGGFCLGVLTPVLNHLTISQNLANSNNSSKANEV 70
            ||.   ||.|:|..:.....|:|.:....||......| |....::.|.|........|::...|
Human    35 LCSGPRLLLLSLGLSLLLLVVVCVIGSQNSQLQEELRG-LRETFSNFTASTEAQVKGLSTQGGNV 98

  Fly    71 LVRQYTMEGQLTALQNKQLSIEVALDAQGRKLNVNEQNFTERLNCMEGILSAL-----EKTVLEV 130
            ..:..::|.||.. |.|.||.:.:      .|.::.:.|...|..:...::||     |:|...|
Human    99 GRKMKSLESQLEK-QQKDLSEDHS------SLLLHVKQFVSDLRSLSCQMAALQGNGSERTCCPV 156

  Fly   131 KTKIKYLGFEQIGSKYYYIEKVSEKNWSTASKTCRNMGGHLADIKDEADLAAIKANLKEDTHYWL 195
            .      ..|...|.|::..  |.|.|:.|...||....||..:....:...::.:: ...:.|:
Human   157 N------WVEHERSCYWFSR--SGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHI-GPVNTWM 212

  Fly   196 GINDLDHEGKFLSMPTGKQTTFLKWASGRPSQLDTL---------NCV-FLYNGEMYDYPCHYTF 250
            |::|.:...|::. .|..:|.|..|   ||.|.|..         :|. |..:|...|..|...:
Human   213 GLHDQNGPWKWVD-GTDYETGFKNW---RPEQPDDWYGHGLGGGEDCAHFTDDGRWNDDVCQRPY 273

  Fly   251 RFICQTE 257
            |::|:||
Human   274 RWVCETE 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lectin-22C	NP_001137766.1	CLECT	146..255	CDD:153057	27/118 (23%)
ASGR1	NP_001662.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		Lectin_N	4..144	CDD:461106	26/116 (22%)
		Endocytosis signal. /evidence=ECO:0000255	5..8
		CLECT_DC-SIGN_like	154..279	CDD:153060	31/137 (23%)