DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-22C and clec-185

DIOPT Version :9

Sequence 1:	NP_001137766.1	Gene:	lectin-22C / 7354375	FlyBaseID:	FBgn0259230	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_502375.4	Gene:	clec-185 / 182914	WormBaseID:	WBGene00007729	Length:	504	Species:	Caenorhabditis elegans

Alignment Length:	203	Identity:	44/203 - (21%)
Similarity:	75/203 - (36%)	Gaps:	51/203 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 LQNKQLSIEVALDAQGRKLNVNEQNFTERLNCMEGILS--------ALEKTVLEV-KTKIKYLGF 139
            |:||.||..:.|:.     :|....:.|||...:|.||        ..:..||.. .|..:|.|
Worm    35 LENKTLSDVIELNQ-----HVQRARYLERLENEKGKLSDEGQQNLVLADGAVLPCDATWHQYSG- 93

  Fly   140 EQIGSKYYYIEKVSEKNWSTASKTCRNMGGHLADIKDEADLAAIKANLKED--------THYWLG 196
              .|..|...::.||  |...::.||       .:..:|.||:..:..:.:        .|.|.|
Worm    94 --TGCCYRTTDEKSE--WYGGTELCR-------ALHPQAQLASFHSQGESEFVCKKYSSIHAWTG 147

  Fly   197 INDLDHEGKFLSMPTGKQTTFLKWASGRPSQLDT-LNCVFLYN-------------GEMYDYPCH 247
            ::..:..|.: :...|  |....|...:.|.:.| .:||.:.:             |:...|.|.
Worm   148 LSQTETPGVW-TYTDG--TPDWHWFFAQSSTMTTEKSCVEMMDGVLVLLFSWSAKKGQTQPYSCT 209

  Fly   248 YTFRFICQ 255
            .:...||:
Worm   210 ESIASICK 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-22C	NP_001137766.1	CLECT	146..255	CDD:153057	24/130 (18%)
clec-185	NP_502375.4	CLECT	84..217	CDD:214480	28/147 (19%)
clec-185	NP_502375.4	CLECT	391..500	CDD:214480
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100