DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lectin-22C and Asgr2

DIOPT Version :9

Sequence 1:	NP_001137766.1	Gene:	lectin-22C / 7354375	FlyBaseID:	FBgn0259230	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001300854.1	Gene:	Asgr2 / 11890	MGIID:	88082	Length:	301	Species:	Mus musculus

Alignment Length:	259	Identity:	56/259 - (21%)
Similarity:	94/259 - (36%)	Gaps:	40/259 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PLKDPPSQ--CGGFCLGVLTPVLNHLTISQNLANSNNSSKANEVLVRQYTMEGQLTALQNKQLSI 91
            ||..|..|  |..|.|.:|....|.|.:......|:.|.:..|..   .|::...:...:..|..
Mouse    44 PLSRPFPQRLCSTFRLSLLALAFNILLLVVICVVSSQSIQLQEEF---RTLKETFSNFSSSTLME 105

  Fly    92 EVALDAQGRKLNVNEQNFTERLNCMEGILSALEKTVL--------EVKTKIKYLGFEQ------- 141
            ..|||..|...|....::..:|...:..|.|...|:|        :::|....|.:.|
Mouse   106 FGALDTLGGSTNAILTSWLAQLEEKQQQLKADHSTLLFHLKHFPMDLRTLTCQLAYFQSNGTECC 170

  Fly   142 ------IGSKYYYIEKVSEKNWSTASKTCRNMGGHLADI--KDEADLAAIKANLKEDTHYWLGIN 198
                  .|...|:..: ....|:.|.:.|:....||..|  ::|.|..   ...:...|.|:|:.
Mouse   171 PVNWVEFGGSCYWFSR-DGLTWAEADQYCQLENAHLLVINSREEQDFV---VKHRSQFHIWIGLT 231

  Fly   199 DLDHEGKFLSMPTGKQTTFLKWASGRP------SQLDTLNCV-FLYNGEMYDYPCHYTFRFICQ 255
            |.|...|::. .|..::.:..||..:|      .|....:|. .|.:|...|..|....|::|:
Mouse   232 DRDGSWKWVD-GTDYRSNYRNWAFTQPDNWQGHEQGGGEDCAEILSDGHWNDNFCQQVNRWVCE 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lectin-22C	NP_001137766.1	CLECT	146..255	CDD:153057	26/117 (22%)
Asgr2	NP_001300854.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43
		Lectin_N	29..162	CDD:281887	27/120 (23%)
		CLECT_DC-SIGN_like	170..295	CDD:153060	28/130 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910