Protein Alignment UCP3 and Dic2

DIOPT Version :10

• Sequence 1: NP_003347.1
• Gene: UCP3 / 7352
• HGNCID: 12519
• Length: 312
• Species: Homo sapiens
• Sequence 2: NP_732513.1
• Gene: Dic2 / 54520426
• FlyBaseID: FBgn0038797
• Length: 304
• Species: Drosophila melanogaster
• Alignment Length: 280
• Identity: 86/280 - (30%)
• Similarity: 139/280 - (49%)
• Gaps: 23/280 - (8%)

Human    21 GTAACFADLVTFPLDTAKVRLQIQGENQAV-QTARLVQYRGVLGTILTMVRTEGPCSPYNGLVAG 84
            |.|:..|.:||.|:|..||.:|.|.|..:| ||.|.:            |:.:||.:.|||:.|.
  Fly    23 GLASSMAAMVTHPIDLIKVLIQTQAEKLSVFQTTRKI------------VKEQGPLAMYNGISAS 75

Human    85 LQRQMSFASIRIGLYDSVKQVYTPKGA-DNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASI 148
            :.||.::...|.|:|.      ...|| |.|::..:.......|.:......|.|::.||.|..:
  Fly    76 MLRQYTYTLARFGIYS------VGSGAMDTSTMAGKTCLAAIAGGIGGFVGAPADLINVRLQNDV 134

Human   149 HLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLL 213
            .|.|.:. |.|...:|....|.||||.:.|:.|:....:|.|.:...::..|:..|.:::... :
  Fly   135 KLPPEKR-RNYKHAIDGLVRITREEGWKNLFNGSSMIALRGAFMTVGQIAFYEQSKSQMIKLG-M 197

Human   214 TDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTP 278
            .|....:.:::..:...||.:..|:||||||.||:.||:|....|..:| .::|||.||:||:.|
  Fly   198 PDYMGTYILASMISSVVATTLTQPIDVVKTRRMNAAPGEYSGLGDVFVK-TSKEGPLAFFKGYVP 261

Human   279 SFLRLGSWNVVMFVTYEQLK 298
            |..||....|::|:..|.|:
  Fly   262 SLSRLLPHTVLLFLGLEYLR 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UCP3	NP_003347.1	Mito_carr	10..110	CDD:395101	28/89 (31%)
		Solcar 1	11..105		28/84 (33%)
		Mito_carr	112..210	CDD:395101	24/97 (25%)
		Solcar 2	114..206		23/91 (25%)
		Mito_carr	214..303	CDD:395101	32/85 (38%)
		Solcar 3	215..300		32/84 (38%)
		Purine nucleotide binding. /evidence=ECO:0000250	279..301		7/20 (35%)
Dic2	NP_732513.1	Mito_carr	22..90	CDD:395101	27/78 (35%)
		Mito_carr	98..194	CDD:395101	24/96 (25%)
		Mito_carr	198..285	CDD:395101	32/85 (38%)