DRSC/TRiP Functional Genomics Resources

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Protein Alignment UCP3 and CG2616

DIOPT Version :10

Sequence 1:NP_003347.1 Gene:UCP3 / 7352 HGNCID:12519 Length:312 Species:Homo sapiens
Sequence 2:NP_649731.1 Gene:CG2616 / 40915 FlyBaseID:FBgn0037512 Length:449 Species:Drosophila melanogaster


Alignment Length:336 Identity:79/336 - (23%)
Similarity:127/336 - (37%) Gaps:73/336 - (21%)


- Green bases have known domain annotations that are detailed below.


Human    19 GAGTAACFADLVTFPLDTAKVRLQIQ---------------------GEN--QAVQTARLVQYRG 60
            ||...|||..    |||..|.|:|.|                     |.|  :.....:..|:..
  Fly   100 GAMITACFMT----PLDVIKTRMQSQQSPAHKCFFYSNGLMDHLFASGPNGSELASLRQRPQFSS 160

Human    61 VLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVK----QVYTP---KGADNSSLTT 118
            ....::.:.|.||..:.::||...|...:....|....|:..|    |:|..   |..:...|..
  Fly   161 SWDALMKISRHEGLAALWSGLGPTLVSALPSTIIYFVAYEQFKARYLQIYESHYNKSQEPRHLEI 225

Human   119 R-----------ILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIARE 172
            |           :::|.|....|||...|.::|:.:.||        ..:.|:..:...|::...
  Fly   226 RDTKKSLPSVVPMMSGVTARICAVTVVSPIELVRTKMQA--------QRQTYAQMLQFVRSVVAL 282

Human   173 EGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASP 237
            :||.|||:|..|.|:|:...:......|:.||:.|  .|....:|...|::...||..|.:|.:|
  Fly   283 QGVWGLWRGLRPTILRDVPFSGIYWPIYESLKQNL--GHGSQPSFSLSFLAGVMAGTVAAIVTTP 345

Human   238 VDVVKTR----------YMNSPPGQY-----FSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWN 287
            .|||||.          :.:||...:     ||.|..:.:   ..|....:.|..|..|::....
  Fly   346 FDVVKTHEQIEFGERVIFTDSPARDFGKKSTFSRLTGIYR---THGVRGLFAGCGPRLLKVAPAC 407

Human   288 VVMFVTYEQLK 298
            .:|..|:|..|
  Fly   408 AIMISTFEYSK 418

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UCP3NP_003347.1 Mito_carr 10..110 CDD:395101 26/120 (22%)
Solcar 1 11..105 24/112 (21%)
Mito_carr 112..210 CDD:395101 26/108 (24%)
Solcar 2 114..206 25/102 (25%)
Mito_carr 214..303 CDD:395101 25/100 (25%)
Solcar 3 215..300 25/99 (25%)
Purine nucleotide binding. /evidence=ECO:0000250 279..301 5/20 (25%)
CG2616NP_649731.1 Mito_carr 86..207 CDD:395101 24/110 (22%)
Mito_carr 230..321 CDD:395101 25/100 (25%)
Mito_carr 321..425 CDD:395101 25/101 (25%)

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