Protein Alignment UCP3 and Dic4

DIOPT Version :10

• Sequence 1: NP_003347.1
• Gene: UCP3 / 7352
• HGNCID: 12519
• Length: 312
• Species: Homo sapiens
• Sequence 2: NP_649054.1
• Gene: Dic4 / 40039
• FlyBaseID: FBgn0036808
• Length: 302
• Species: Drosophila melanogaster
• Alignment Length: 293
• Identity: 84/293 - (28%)
• Similarity: 143/293 - (48%)
• Gaps: 20/293 - (6%)

Human     8 DVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTE 72
            |.|..:..::...|.|:........|:|..|..:|||.           |.|.:|||:..:...:
  Fly    14 DEPEGLLPRWWFGGFASMCVAFAVAPIDIVKTHMQIQR-----------QKRSILGTVKRIHSLK 67

Human    73 GPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQPT 137
            |....|:|..|.:.|||:..:|...:||:.|::   :..|..|...:|:.||..||.......||
  Fly    68 GYLGFYDGFSAAILRQMTSTNIHFIVYDTGKKM---EYVDRDSYLGKIILGCVAGACGSAFGIPT 129

Human   138 DVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDI 202
            |::.||.|..:...|.:. |.|....|....|.:|||.:.|:||....:.::::..|:::..|||
  Fly   130 DLINVRMQTDMKEPPYKR-RNYKHVFDGLIRIPKEEGWKALYKGGSVAVFKSSLSTCSQIAFYDI 193

Human   203 LKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPPGQYFSPLDCMIKMV--A 265
            :|.::.....:.|..|.||:::.|....::.:..|:|||:|..|||.||::.:.....:.|:  .
  Fly   194 IKTEVRKNISVNDGLPLHFLTSLGTSIISSAITHPLDVVRTIMMNSRPGEFRTVFQASVHMMRFG 258

Human   266 QEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLK 298
            ..||   |:||.|:.:|......::||.||||:
  Fly   259 VMGP---YRGFVPTIVRKAPATTLLFVLYEQLR 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UCP3	NP_003347.1	Mito_carr	10..110	CDD:395101	25/99 (25%)
		Solcar 1	11..105		24/93 (26%)
		Mito_carr	112..210	CDD:395101	29/97 (30%)
		Solcar 2	114..206		28/91 (31%)
		Mito_carr	214..303	CDD:395101	29/87 (33%)
		Solcar 3	215..300		29/86 (34%)
		Purine nucleotide binding. /evidence=ECO:0000250	279..301		7/20 (35%)
Dic4	NP_649054.1	Mito_carr	26..100	CDD:395101	24/84 (29%)
		Mito_carr	104..201	CDD:395101	29/97 (30%)
		Mito_carr	211..292	CDD:395101	27/81 (33%)