Protein Alignment UCP3 and Dic3

DIOPT Version :10

• Sequence 1: NP_003347.1
• Gene: UCP3 / 7352
• HGNCID: 12519
• Length: 312
• Species: Homo sapiens
• Sequence 2: NP_610344.2
• Gene: Dic3 / 35763
• FlyBaseID: FBgn0033248
• Length: 287
• Species: Drosophila melanogaster
• Alignment Length: 280
• Identity: 95/280 - (33%)
• Similarity: 138/280 - (49%)
• Gaps: 20/280 - (7%)

Human    21 GTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMV-RTEGPCSPYNGLVAG 84
            |..|..|...|.|:|..||:||.|.:..          |..:|.||..: ...|....|||:.|.
  Fly    16 GVCAAIAVTGTHPIDLIKVQLQTQSQAD----------RKTVGEILKGIHERSGILGFYNGISAS 70

Human    85 LQRQMSFASIRIGLYDSVKQ-VYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASI 148
            ..||:::.:.|..||::.|. |.|.|.:...:|.|  .||...|.:.|    |.|||.||.|..:
  Fly    71 WFRQLTYTTTRFALYEAGKDYVDTQKVSSKMALAT--FAGIVGGIVGV----PGDVVTVRLQNDV 129

Human   149 HLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLL 213
            .| |....|.|....|....|.:||||..|::||:|.:.|..::.......||.:|:.|......
  Fly   130 KL-PEEKRRNYKHVFDGLFRIYKEEGVSSLFRGTVPAVSRAVLLTIGTNAAYDQVKQMLKIATGA 193

Human   214 TDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTP 278
            .:..|.||.::..||..|.|:..|:||:||.:||:.||: ||.:.......|::||.||||||.|
  Fly   194 GEGVPLHFATSTIAGCIAVVITQPLDVIKTTFMNAQPGE-FSGIGGAFLSTAKQGPLAFYKGFIP 257

Human   279 SFLRLGSWNVVMFVTYEQLK 298
            :.:|:....::.||.|||.:
  Fly   258 ALIRVSPNTIITFVLYEQAR 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UCP3	NP_003347.1	Mito_carr	10..110	CDD:395101	28/90 (31%)
		Solcar 1	11..105		26/85 (31%)
		Mito_carr	112..210	CDD:395101	32/97 (33%)
		Solcar 2	114..206		31/91 (34%)
		Mito_carr	214..303	CDD:395101	34/85 (40%)
		Solcar 3	215..300		34/84 (40%)
		Purine nucleotide binding. /evidence=ECO:0000250	279..301		6/20 (30%)
Dic3	NP_610344.2	Mito_carr	15..91	CDD:395101	26/84 (31%)
		Mito_carr	93..187	CDD:395101	33/100 (33%)
		Mito_carr	200..281	CDD:395101	33/79 (42%)