| Sequence 1: | NP_003346.2 | Gene: | UCP2 / 7351 | HGNCID: | 12518 | Length: | 309 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_650279.1 | Gene: | Dic1 / 41640 | FlyBaseID: | FBgn0027610 | Length: | 280 | Species: | Drosophila melanogaster |
| Alignment Length: | 293 | Identity: | 54/293 - (18%) |
|---|---|---|---|
| Similarity: | 94/293 - (32%) | Gaps: | 81/293 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Human 372 LGHDFHVFQILTHPWSSSQCAVHHLYTLHRGETEAKVQDI-------------CFSHDCRWVVVS 423
Human 424 TLRGTSHVFPINPYGGQPC-VRTHMSPRVVNRMS---------RFQKSAGLEEIEQELTSKQGGR 478
Human 479 CSPVPGLSSSPSGSPLHGKLSSQD----SYNNFTNNNPG-NPRLSPLPSLMVV------------ 526
Human 527 -TPLAQIKQPMTLGTITKRTGPYLFGAGCFSIKAPCKVKPPPQISPSKS--------MGGEFCVA 582
Human 583 AVFGTSRSWFANNAGLKREKDQSKQVVVESLYI 615 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| UCP2 | NP_003346.2 | Mito_carr | 10..111 | CDD:395101 | |
| Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 | 11..106 | ||||
| Important for interaction with long-chain fatty acids. /evidence=ECO:0000250|UniProtKB:P70406 | 16..63 | ||||
| transmembrane domain | 17..34 | ||||
| transmembrane domain | 78..100 | ||||
| Mito_carr | 112..206 | CDD:395101 | |||
| Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 | 114..203 | ||||
| transmembrane domain | 120..137 | ||||
| transmembrane domain | 174..197 | ||||
| Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 | 212..297 | ||||
| transmembrane domain | 216..235 | ||||
| Mito_carr | 217..299 | CDD:395101 | |||
| purine nucleotide binding domain | 264..273 | ||||
| transmembrane domain | 269..291 | ||||
| Important for interaction with long-chain fatty acids. /evidence=ECO:0000250|UniProtKB:P70406 | 278..285 | ||||
| Dic1 | NP_650279.1 | Mito_carr | 10..92 | CDD:395101 | 2/4 (50%) |
| Mito_carr | 89..184 | CDD:395101 | 13/99 (13%) | ||
| Mito_carr | 189..278 | CDD:395101 | 20/96 (21%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||