DRSC/TRiP Functional Genomics Resources

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Protein Alignment UCP2 and CG16736

DIOPT Version :10

Sequence 1:NP_003346.2 Gene:UCP2 / 7351 HGNCID:12518 Length:309 Species:Homo sapiens
Sequence 2:NP_649873.1 Gene:CG16736 / 41101 FlyBaseID:FBgn0037668 Length:277 Species:Drosophila melanogaster


Alignment Length:11 Identity:7/11 - (63%)
Similarity:9/11 - (81%) Gaps:1/11 - (9%)


- Green bases have known domain annotations that are detailed below.


Human   454 RMSRFQK-SAG 463
            |.:|||: |||
  Fly    81 RSNRFQQPSAG 91

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UCP2NP_003346.2 Mito_carr 10..111 CDD:395101
Solcar 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 11..106
Important for interaction with long-chain fatty acids. /evidence=ECO:0000250|UniProtKB:P70406 16..63
transmembrane domain 17..34
transmembrane domain 78..100
Mito_carr 112..206 CDD:395101
Solcar 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 114..203
transmembrane domain 120..137
transmembrane domain 174..197
Solcar 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00282 212..297
transmembrane domain 216..235
Mito_carr 217..299 CDD:395101
purine nucleotide binding domain 264..273
transmembrane domain 269..291
Important for interaction with long-chain fatty acids. /evidence=ECO:0000250|UniProtKB:P70406 278..285
CG16736NP_649873.1 Mito_carr 6..81 CDD:395101 7/11 (64%)
Mito_carr 187..277 CDD:395101
Blue background indicates that the domain is not in the aligned region.

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