Protein Alignment UCP2 and Ucp4A

DIOPT Version :9

• Sequence 1: XP_024304442.1
• Gene: UCP2 / 7351
• HGNCID: 12518
• Length: 310
• Species: Homo sapiens
• Sequence 2: NP_001188664.1
• Gene: Ucp4A / 32764
• FlyBaseID: FBgn0030872
• Length: 340
• Species: Drosophila melanogaster
• Alignment Length: 280
• Identity: 97/280 - (34%)
• Similarity: 150/280 - (53%)
• Gaps: 10/280 - (3%)

Human    33 YPCSYPVLALQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVR 97
            ||.......||||||........::.||||::.|...:.|.||...|:.|:...|.|.:.::.||
  Fly    59 YPLDLTKTRLQIQGEGAAHSAGKSNMQYRGMVATAFGIAREEGALKLWQGVTPALYRHVVYSGVR 123

Human    98 IGLYDSV-KQFYTKGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQAR---AGGGRRYQ 158
            |..||.: |:|...|::...:....|.|.|.||:|..:|.|.|:|||:.|.:.|   .|...|..
  Fly   124 ICSYDLMRKEFTQNGTQALPVWKSALCGVTAGAVAQWLASPADLVKVQIQMEGRRRLMGEPPRVH 188

Human   159 STVNAYKTIAREEGFRGLWKGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAF 223
            |..:|::.|.:..|.:|||||:.|||.|.|:||..:|.|||.||..::....|.|....|..::.
  Fly   189 SAGHAFRQIVQRGGIKGLWKGSIPNVQRAALVNLGDLTTYDTIKHLIMNRLQMPDCHTVHVLASV 253

Human   224 GAGFCTTVIASPVDVVKTRYMNSALGQ------YSSAGHCALTMLQKEGPRAFYKGFMPSFLRLG 282
            .|||...::.:|.||||||.||....:      |..:..|....:.|||..|.||||:|.::|:.
  Fly   254 CAGFVAAIMGTPADVVKTRIMNQPTDENGRGLLYRGSVDCLRQTVSKEGFVALYKGFLPCWIRMA 318

Human   283 SWNVVMFVTYEQLKRALMAA 302
            .|::..::::||:::.:.|:
  Fly   319 PWSLTFWLSFEQIRKMIGAS 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UCP2	XP_024304442.1	Mito_carr	<42..112	CDD:332982	25/70 (36%)
		Mito_carr	113..207	CDD:278578	38/96 (40%)
		Mito_carr	218..300	CDD:278578	28/87 (32%)
Ucp4A	NP_001188664.1	PTZ00169	39..335	CDD:240302	96/275 (35%)
		Mito_carr	39..138	CDD:278578	27/78 (35%)
		Mito_carr	142..239	CDD:278578	38/96 (40%)
		Mito_carr	248..336	CDD:278578	28/87 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0759
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810