Protein Alignment UCHL3 and YUH1

DIOPT Version :10

• Sequence 1: XP_011533514.1
• Gene: UCHL3 / 7347
• HGNCID: 12515
• Length: 294
• Species: Homo sapiens
• Sequence 2: NP_012633.1
• Gene: YUH1 / 853562
• SGDID: S000003860
• Length: 236
• Species: Saccharomyces cerevisiae
• Alignment Length: 300
• Identity: 82/300 - (27%)
• Similarity: 127/300 - (42%)
• Gaps: 82/300 - (27%)

Human     2 EGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGM-DPELLSMVPRPVCAVLLLFPITEKYEVF 65
            |.:..:|:|:||||...|..:|||...|.:.|:|.: :||||:.:||||.|::|||||
Yeast     4 ENRAVVPIESNPEVFTNFAHKLGLKNEWAYFDIYSLTEPELLAFLPRPVKAIVLLFPI------- 61

Human    66 RTEEEEKIKSQGQDVTSS--VYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVS 128
               .|::..|..|.:|||  |.:.||::.||||...::|:::||:..:  |.||.|..||:
Yeast    62 ---NEDRKSSTSQQITSSYDVIWFKQSVKNACGLYAILHSLSNNQSLL--EPGSDLDNFLK---- 117

Human   129 MSPEERARYLENYDAIRVTHETSAHEGQTESSSPSSSQPHSSHCRTKASSLCHHASLPWVKRNHV 193
                                         ..|..|||:.......|      ....|..:|.|
Yeast   118 -----------------------------SQSDTSSSKNRFDDVTT------DQFVLNVIKEN-- 145

Human   194 GPAKATSPSLRLRRWRPFLRLPSLGLHSVAPSIDEKVDLHFIALVHVDGHLYELDGRK---PFPI 255
                              ::..|.| .|.||......:||:|..|..:|.::|||||.   |..:
Yeast   146 ------------------VQTFSTG-QSEAPEATADTNLHYITYVEENGGIFELDGRNLSGPLYL 191

Human   256 NHGETSDETLLEDAIEVCK--KFME--RDPDELRFNAIAL 291
            ...:.:...|:|..:...:  .:||  .:.|.|.|..:.|
Yeast   192 GKSDPTATDLIEQELVRVRVASYMENANEEDVLNFAMLGL 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UCHL3	XP_011533514.1	Peptidase_C12_UCH_L1_L3	6..291	CDD:187737	80/294 (27%)
YUH1	NP_012633.1	Peptidase_C12	8..231	CDD:471809	80/294 (27%)