Protein Alignment UCHL3 and ubh-3

DIOPT Version :10

• Sequence 1: XP_011533514.1
• Gene: UCHL3 / 7347
• HGNCID: 12515
• Length: 294
• Species: Homo sapiens
• Sequence 2: NP_504653.2
• Gene: ubh-3 / 259626
• WormBaseID: WBGene00006723
• Length: 227
• Species: Caenorhabditis elegans
• Alignment Length: 288
• Identity: 85/288 - (29%)
• Similarity: 131/288 - (45%)
• Gaps: 74/288 - (25%)

Human     6 WLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEE 70
            |..||:|||..|.|||::|: ...:.||||..|.|:|..||.|..|::|.||..|..| |.:::.
 Worm     9 WQALESNPETINPFLKKIGI-TGLECVDVYSFDDEMLQFVPTPQLALILCFPSAEARE-FLSKQY 71

Human    71 EKIKSQGQDVTSSVYFMKQT--ISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEE 133
            |:::..|:. ...|:||.|:  |.|||||..|.|::||.:::::...|. ..|:.|::..::.:|
 Worm    72 EEVEKNGEK-PEGVFFMNQSEEIGNACGTFALFHSLANLENRVNLGKGK-FAKWYEKAKLVNEDE 134

Human   134 RARYLENYDAIRVTHETSAHEGQTESSSPSSSQPHSSHCRTKASSLCHHASLPWVKRNHVGPAKA 198
            |:..|.....:...||.:|.||:||.|
 Worm   135 RSDLLSGDTDLAEAHEETAEEGETEQS-------------------------------------- 161

Human   199 TSPSLRLRRWRPFLRLPSLGLHSVAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDE 263
                                         :.||.|||..|:.:|.|||:|...|||...|.|:|.
 Worm   162 -----------------------------DHVDYHFITYVNKNGQLYEIDSCAPFPRPLGATTDS 197

Human   264 TLLEDAIEVCKKFMERDPDELRFNAIAL 291
            |:::||....|:.| .:...|.|:|:||
 Worm   198 TMIKDASTAIKELM-NNVKNLSFSAMAL 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UCHL3	XP_011533514.1	Peptidase_C12_UCH_L1_L3	6..291	CDD:187737	83/286 (29%)
ubh-3	NP_504653.2	Peptidase_C12_UCH_L1_L3	9..224	CDD:187737	83/286 (29%)