Protein Alignment UCHL3 and uch1

DIOPT Version :10

• Sequence 1: XP_011533514.1
• Gene: UCHL3 / 7347
• HGNCID: 12515
• Length: 294
• Species: Homo sapiens
• Sequence 2: NP_594531.1
• Gene: uch1 / 2541733
• PomBaseID: SPAC27F1.03C
• Length: 222
• Species: Schizosaccharomyces pombe
• Alignment Length: 291
• Identity: 73/291 - (25%)
• Similarity: 118/291 - (40%)
• Gaps: 76/291 - (26%)

Human     6 WLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEE 70
            |.|||..|||...:|:::|:.....| |::.:: |:...:||||.|:|.:||.:....:::   .
pombe     2 WRPLENTPEVLEPYLQKIGVQDASVF-DLFSLE-EIPEYIPRPVHALLFVFPSSGTKTIYK---G 61

Human    71 EKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERA 135
            .:|..:..|   .|.:..|||.||||||||:||::|.:.:........:|..:..:...|.||||
pombe    62 SRILPKDSD---KVLWYPQTIPNACGTIGLLHAVSNGELRRKVNENDFIKSLIRTAEGSSIEERA 123

Human   136 RYLENYDAIRVTHETSAHEGQTESSSPSSSQPHSSHCRTKASSLCHHASLPWVKRNHVGPAKATS 200
            :.:|:...:...|...|                                         ||.
pombe   124 KLIEDSKELEALHAAFA-----------------------------------------GPP---- 143

Human   201 PSLRLRRWRPFLRLPSLGLHSVAPSIDEKVDLHFIALV----HVDGHLYELDGRKPFPINHGETS 261
                              |.......|.:.|||||..|    ..|.|.||||||:..|:.|.|..
pombe   144 ------------------LEVEGSEEDVETDLHFICFVKGKSKDDNHFYELDGRQEGPVQHSEIE 190

Human   262 DETLLEDAIEVCKKFMERDPDELRFNAIALS 292
            .:.|..:.:.|.|.::: ..|...|:.:|::
pombe   191 SDLLNAEVLSVIKNYIQ-SIDSPFFSLVAIT 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UCHL3	XP_011533514.1	Peptidase_C12_UCH_L1_L3	6..291	CDD:187737	72/288 (25%)
uch1	NP_594531.1	Peptidase_C12_UCH_L1_L3	2..219	CDD:187737	72/288 (25%)