Protein Alignment UCHL3 and ubh-2

DIOPT Version :10

• Sequence 1: XP_011533514.1
• Gene: UCHL3 / 7347
• HGNCID: 12515
• Length: 294
• Species: Homo sapiens
• Sequence 2: NP_001294721.2
• Gene: ubh-2 / 24105081
• WormBaseID: WBGene00006722
• Length: 227
• Species: Caenorhabditis elegans
• Alignment Length: 288
• Identity: 77/288 - (26%)
• Similarity: 127/288 - (44%)
• Gaps: 73/288 - (25%)

Human     6 WLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEE 70
            |..||:|||..|.||.::|: ...:.|||:..|.|:|..:|.|..|::|.||.:...| ||.::.
 Worm     8 WQALESNPETINPFLSKIGV-SGVECVDVFSFDDEMLQFIPTPQLALILCFPSSGVRE-FRAKQY 70

Human    71 EKIKSQGQDVTSSVYFM--KQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEE 133
            |:::..|:. ...::||  |:.|.:||||..|.|::||.:::::..:|. ..|:.|::..:...|
 Worm    71 EEVEKNGKK-PDGIFFMNQKKEIGHACGTFSLFHSLANLENRVNLGNGK-FSKWFEKAKLVGEGE 133

Human   134 RARYLENYDAIRVTHETSAHEGQTESSSPSSSQPHSSHCRTKASSLCHHASLPWVKRNHVGPAKA 198
            |:..|.....:...|:.:|.||:||         |..|
 Worm   134 RSDLLLADTDLAEAHKETAEEGETE---------HPEH--------------------------- 162

Human   199 TSPSLRLRRWRPFLRLPSLGLHSVAPSIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDE 263
                                           |..|||..|:.:|.|:|:|...|||...|.|:|.
 Worm   163 -------------------------------VAYHFITYVNKNGQLFEIDSCSPFPRPLGATTDS 196

Human   264 TLLEDAIEVCKKFMERDPDELRFNAIAL 291
            |::.||.....|.:..:..:|.|:|:||
 Worm   197 TMIRDAFSTSIKDLMDNVQKLSFSAMAL 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UCHL3	XP_011533514.1	Peptidase_C12_UCH_L1_L3	6..291	CDD:187737	75/286 (26%)
ubh-2	NP_001294721.2	Peptidase_C12_UCH_L1_L3	8..224	CDD:187737	75/286 (26%)