Protein Alignment UCHL1 and ubh-1

DIOPT Version :10

• Sequence 1: NP_004172.2
• Gene: UCHL1 / 7345
• HGNCID: 12513
• Length: 223
• Species: Homo sapiens
• Sequence 2: NP_504654.1
• Gene: ubh-1 / 179039
• WormBaseID: WBGene00006721
• Length: 216
• Species: Caenorhabditis elegans
• Alignment Length: 215
• Identity: 81/215 - (37%)
• Similarity: 123/215 - (57%)
• Gaps: 8/215 - (3%)

Human     5 PMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEE 69
            |:|.||.::|.::.::||:|. :.||||..::||:|.   |..|::|.||...:.:...|...|:
 Worm     7 PLESNPSVINPMIEKMGVSGV-KTVDVLFFDDESIGK---PQHAVILCFPEYKKVDEIMKPIYEQ 67

Human    70 LKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETEKMSPEDRAKCFE 134
            .|..:.|  |:||||.|.|:|||..|.|::||.:|::...|||..| :|:|.:|:..|:|:....
 Worm    68 AKAADDS--VFFMKQKISNACGTFALFHSLANLEDRINLGDGSFAK-WLAEAKKVGIEERSDFLA 129

Human   135 KNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDTLLKDAAK 199
            .|..:...|.|.|.:||......|..|||.|...:|.|||:|.|.||....|.:|:.||:|||..
 Worm   130 NNAELAGIHAAAATDGQTAPSGDVEHHFICFVGKNGILYEIDSRRPFAREIGPTSDATLVKDAGA 194

Human   200 VCREFTEREQGEVRFSAVAL 219
            .|:...|: ...|.|||:|:
 Worm   195 ACQHLIEK-LDNVSFSAIAV 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UCHL1	NP_004172.2	Peptidase_C12_UCH_L1_L3	5..219	CDD:187737	80/213 (38%)
		Interaction with ubiquitin. /evidence=ECO:0000269|PubMed:20439756	5..10		2/4 (50%)
		Interaction with ubiquitin. /evidence=ECO:0000269|PubMed:20439756	211..216		2/4 (50%)
ubh-1	NP_504654.1	Peptidase_C12_UCH_L1_L3	5..212	CDD:187737	80/212 (38%)