Protein Alignment UBTF and ubtf

DIOPT Version :10

• Sequence 1: NP_055048.1
• Gene: UBTF / 7343
• HGNCID: 12511
• Length: 764
• Species: Homo sapiens
• Sequence 2: NP_001005395.1
• Gene: ubtf / 368509
• ZFINID: ZDB-GENE-030616-252
• Length: 735
• Species: Danio rerio
• Alignment Length: 770
• Identity: 500/770 - (64%)
• Similarity: 617/770 - (80%)
• Gaps: 41/770 - (5%)

Human     1 MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSG 65
            ||||.|......:        |.|:|:|.||:.||.|||..|.:|:||:|||:|||||||..:|.
Zfish     1 MNGEMDSSAKATV--------WVQDDVLKLLDAMKVNLPEKDLAKYKTSESHLDWEKVAFDAYSA 57

Human    66 DMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKY 130
            ::||.||.|:|.|:||||||||||:|||:::||||||||||||||||||||||||||||||||||
Zfish    58 EVCKQKWQEVSREIRKFRTLTELIVDAQDYIKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKY 122

Human   131 AKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNA-KKSD 194
            ||||||||||||||||||||||||::||.||::||.|||:.|..::.:|:::||||::|. |||:
Zfish   123 AKLHPEMSNLDLTKILSKKYKELPDRKKEKYVKDFLREKETFMLSMMKFKQEHPDLLENVNKKSN 187

Human   195 IPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEI 259
            :|||.||||||||:||||.:||..||||||::||:|||||.|||||||:|||.|:|||.|.|||.
Zfish   188 VPEKAKTPQQLWYSHEKKAFLKAHPDATTKDIKDNLGKQWPQLSDKKRIKWIAKSLEQHKLYEEK 252

Human   260 MRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTER 324
            ||::||:|||:|:::..|.||:||||||||||||||||.|||.|.|||:|||||::|||||||||
Zfish   253 MREFIQQHPEMNMTQGDIVKSSLTKAERQLKDKFDGRPDKPPSNGYSLFCAELMSSMKDVPSTER 317

Human   325 MVLCSQQWKLLSQKEKDAYHKKCDQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQA-T 388
            ||:|||:||||.|.|||||.|:|:||||:||||:.|:|.|:.||||||:|.|:||.:..|... :
Zfish   318 MVMCSQRWKLLKQAEKDAYQKRCEQKKKEYEVEMNRYLLSISEEEQQRILSEQKMGSFKKAGGIS 382

Human   389 SPASKKPAQEGGKGGSEKPKRPVSAMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKK 453
            ||||||.:.: .|..:||||.|:|||||||||||.:|::|:||||:.|||||||||||:|::|||
Zfish   383 SPASKKKSSK-AKPSAEKPKPPISAMFIFSEEKRPKLKQEKPELSDMELTRLLARMWNELTDKKK 446

Human   454 AKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMT 518
            .|||..|.||||::|::   .|||:|||||:||.|:|||||||||||||||||||.||.|.||.|
Zfish   447 EKYKTLEMALKAEAEKQ---SREEKGKLPETPKTAQEIWQQSVIGDYLARFKNDRAKAQKTMEAT 508

Human   519 WNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQELL 583
            ||.||||||::||||||||||||||||||||:|.......|||||.|||||||.|||||||||:|
Zfish   509 WNTMEKKEKIVWIKKAAEDQKRYERELSEMRSPAPVITPGKKMKFDGEPKKPPSNGYQKFSQEML 573

Human   584 SNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEY 648
            |||||||||:||||.|||.||||:.|..|:.||::|||:|:.|||.|:.|:.|:|.|:|||||||
Zfish   574 SNGELNHLPMKERMGEIGGRWQRLPQKDKDRYKRIAEEKQRLYKVELEQWLTSISSQERAAYKEY 638

Human   649 ISNKRKSMTKLRGPN----PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDS 709
            .|.||:|..|..|.|    ||:.|:          |||||||::|:||:::.|.:|.||:|
Zfish   639 NSLKRRSTAKPGGTNAKVKPKAKRS----------DDEEDEDEDDDDEDDDKDSDGSSSDD---- 689

Human   710 SESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
               |.:|:.:|.::||||.|||:.|     |::|:|| ||||||||.|||.|||:
Zfish   690 ---SDDDDDDDDEDNEEDVEDEEVD-----DKENKSE-SSSSSSSSDDSSASDSD 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UBTF	NP_055048.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		5/19 (26%)
		HMG-box_UBF1_rpt1-like	109..185	CDD:438814	58/75 (77%)
		HMG-box_UBF1_rpt2	196..270	CDD:438815	54/73 (74%)
		HMG-box_UBF1_rpt3	297..379	CDD:438816	58/81 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	381..411		12/30 (40%)
		HMG-box_UBF1_rpt4	405..470	CDD:438817	46/64 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	459..487		15/27 (56%)
		HMG_box_5	479..562	CDD:434287	64/82 (78%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	546..576		19/29 (66%)
		HMG-box_UBF1_rpt6-like	565..650	CDD:438819	60/84 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	648..764		54/119 (45%)
ubtf	NP_001005395.1	HMG-box_UBF1_rpt1-like	101..177	CDD:438814	58/75 (77%)
		HMG-box_UBF1_rpt2	189..262	CDD:438815	53/72 (74%)
		HMG-box_UBF1_rpt3	290..372	CDD:438816	58/81 (72%)
		HMG-box_UBF1_rpt4	398..463	CDD:438817	46/64 (72%)
		HMG-box_SF	469..552	CDD:469606	64/82 (78%)
		HMG-box_UBF1_rpt6-like	555..640	CDD:438819	60/84 (71%)