DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment UBE2E2 and Ubc2

DIOPT Version :9

Sequence 1:	NP_001357154.1	Gene:	UBE2E2 / 7325	HGNCID:	12478	Length:	201	Species:	Homo sapiens
Sequence 2:	NP_001260362.1	Gene:	Ubc2 / 34487	FlyBaseID:	FBgn0015320	Length:	232	Species:	Drosophila melanogaster

Alignment Length:	215	Identity:	153/215 - (71%)
Similarity:	166/215 - (77%)	Gaps:	24/215 - (11%)

- Green bases have known domain annotations that are detailed below.

Human     2 STEAQRVDDS--PSTSG-------------GSSDGDQRESVQQEPEREQVQPKKKEGKISSKTAA 51
            ||.|..|.::  |:|:|             |.:.|..... ..||        :||.|.:.:.:.
  Fly    27 STTASNVSNTSQPTTAGTPQARGGRGSNANGGASGSNAGG-GDEP--------RKEAKTTPRISR 82

Human    52 KLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSPDYPF 116
            .|.|||||||||||||||||||||||||||||:|||.||||||||||||||||||||.|||:|||
  Fly    83 ALGTSAKRIQKELAEITLDPPPNCSAGPKGDNLYEWVSTILGPPGSVYEGGVFFLDIHFSPEYPF 147

Human   117 KPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQY 181
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   148 KPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQY 212

Human   182 MTNRAEHDRMARQWTKRYAT 201
            :.||.||||:||.|||||||
  Fly   213 LQNREEHDRIARLWTKRYAT 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UBE2E2	NP_001357154.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55		15/67 (22%)
UBE2E2	NP_001357154.1	UQ_con	59..196	CDD:395127	127/136 (93%)
Ubc2	NP_001260362.1	COG5078	86..231	CDD:227410	135/144 (94%)
Ubc2	NP_001260362.1	UQ_con	90..227	CDD:278603	127/136 (93%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	271	1.000	Domainoid score	I1821
eggNOG	1	0.900	-	-		E2759_KOG0417
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H77337
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2691
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53976
OrthoDB	1	1.010	-	-		D1337945at2759
OrthoFinder	1	1.000	-	-		FOG0002573
OrthoInspector	1	1.000	-	-		otm40329
orthoMCL	1	0.900	-	-		OOG6_103488
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4811
SonicParanoid	1	1.000	-	-		X1929
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870