DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment UBE2E2 and CG2574

DIOPT Version :9

Sequence 1:	NP_001357154.1	Gene:	UBE2E2 / 7325	HGNCID:	12478	Length:	201	Species:	Homo sapiens
Sequence 2:	NP_572796.1	Gene:	CG2574 / 32190	FlyBaseID:	FBgn0030386	Length:	239	Species:	Drosophila melanogaster

Alignment Length:	184	Identity:	87/184 - (47%)
Similarity:	115/184 - (62%)	Gaps:	10/184 - (5%)

- Green bases have known domain annotations that are detailed below.

Human    27 VQQEPE----------REQVQPKKKEGKISSKTAAKLSTSAKRIQKELAEITLDPPPNCSAGPKG 81
            |:.|||          .|:..|..........|.|.|:....||:.||.:|..:|||||:|....
  Fly    24 VEVEPEVLSRASVASSVEETAPSTSHSASGKSTEAPLTGCVVRIKSELQDIRKNPPPNCTADLHH 88

Human    82 DNIYEWRSTILGPPGSVYEGGVFFLDITFSPDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDN 146
            .::..|.:.:.||.|||||||.|.|||.|...|||:.|::.|.|||||||::|:|.||||:|.:.
  Fly    89 GDLLHWTAGVNGPVGSVYEGGHFRLDIRFPASYPFRAPRIRFTTRIYHCNVDSRGAICLDVLGER 153

Human   147 WSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQWTKRYA 200
            |||.:.::||||||..|:::|||.||||..||.||.|||.|||::||.|||.:|
  Fly   154 WSPVMNVAKVLLSIYVLMSECNPDDPLVMCIADQYKTNRREHDKIARHWTKLFA 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UBE2E2	NP_001357154.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55		9/37 (24%)
UBE2E2	NP_001357154.1	UQ_con	59..196	CDD:395127	74/136 (54%)
CG2574	NP_572796.1	COG5078	66..208	CDD:227410	78/142 (55%)
CG2574	NP_572796.1	UQ_con	66..203	CDD:278603	74/136 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0417
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1337945at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24068
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920