DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment UBE2B and Ubc4

DIOPT Version :9

Sequence 1:	NP_003328.1	Gene:	UBE2B / 7320	HGNCID:	12473	Length:	152	Species:	Homo sapiens
Sequence 2:	NP_001287013.1	Gene:	Ubc4 / 39133	FlyBaseID:	FBgn0015321	Length:	199	Species:	Drosophila melanogaster

Alignment Length:	156	Identity:	48/156 - (30%)
Similarity:	83/156 - (53%)	Gaps:	9/156 - (5%)

- Green bases have known domain annotations that are detailed below.

Human     1 MSTPARRRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAV---IFGPEGTPFEDGTFKLVIEFSEE 62
            |:..|..|:.|:||.:.....:.......|.....|..:   |.||..||:|.|.|.|.|:..|.
  Fly     1 MANMAVSRIKREFKEVMRSEEIVQCSIKIELVNDSWTELRGEIAGPPDTPYEGGKFVLEIKVPET 65

Human    63 YPNKPPTVRFLSKMFHPNVYA-DGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQA 126
            ||..||.|||:::::|||:.: .|:||||||::.|:....:.::|.|:|:||....|:.|.::..
  Fly    66 YPFNPPKVRFITRIWHPNISSVTGAICLDILKDNWAAAMTLRTVLLSLQALLAAAEPDDPQDAVV 130

Human   127 AQLYQENKREYEKRVSAIVEQSWNDS 152
            |..:   |.:|:  :..:..:.|.::
  Fly   131 AYQF---KDKYD--LFLLTAKHWTNA 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UBE2B	NP_003328.1	UQ_con	8..145	CDD:395127	45/140 (32%)
Ubc4	NP_001287013.1	COG5078	1..153	CDD:227410	48/156 (31%)
		UQ_con	8..149	CDD:278603	45/145 (31%)
		UBA_II_E2_UBCD4	163..198	CDD:270574
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910