Protein Alignment CIMIP2B and CG18335

DIOPT Version :10

• Sequence 1: NP_001274168.1
• Gene: CIMIP2B / 730112
• HGNCID: 34242
• Length: 306
• Species: Homo sapiens
• Sequence 2: NP_610666.1
• Gene: CG18335 / 36202
• FlyBaseID: FBgn0033610
• Length: 323
• Species: Drosophila melanogaster
• Alignment Length: 323
• Identity: 74/323 - (22%)
• Similarity: 112/323 - (34%)
• Gaps: 101/323 - (31%)

Human    11 LNPQNPHYIPGYTGHCPLLRFSVGQTYGQVTGQLLRGP-----PGLAWPPVH--RTLLPPIRPPR 68
            :.|: ||.:|||||||...|..||:|||:.|.:||..|     |.|...|:|  |.|
  Fly     5 ITPE-PHLVPGYTGHCAQNRDRVGRTYGRQTHKLLIDPCIYHAPELIVAPIHAKRGL-------- 60

Human    69 SPEVPRE-SLPVRRGQERLSSS-----MIPGYTGFVPR------AQFIFAKNCSQVWAEALSDFT 121
             .:.|.| .|.:.|.:|.|..|     ::|||.||||.      .:::.|.:......|.|.:..
  Fly    61 -KDYPTEQELKILRTREGLVDSVYRHPILPGYAGFVPNKVSQIGKRYVAAASAGVARHETLMELY 124

Human   122 HLHEKQ-GSEELPKEAKGRKDTEKDQVPEPEGQLEEPTLEVV---------------------EQ 164
            ....:. ...:|.:...|..|.:.::...|:.....|.:.|.                     :.
  Fly   125 RCENRTLRHRDLLESGNGLFDRKINERLLPQTYYRSPLILVTGVSKGIKDETCPPKTEKLCYSKF 189

Human   165 ASPYSMDDRDPRKFFMSAF----------------------LCS--------------------- 186
            .||:.::|.|..||.::.:                      |||
  Fly   190 TSPHFLEDEDADKFIINGYSGHIPMSVTRFGESNKVLTNRALCSFSDYMYKRKRDTWCCGQDLSR 254

Human   187 PTRHCRNLGRST--HQAVPRTPNISPHFPEHTLRTWVFYLTMGATCQGISSSLATH--LAISP 245
            |:..|..:|...  |:.....||.:.|.|..|.:   |..|...|.......|..|  |.:.|
  Fly   255 PSITCPPVGHFVVYHEDSGMVPNYAGHVPGETYK---FGRTYAKTTYDAKRWLEVHKNLTVLP 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CIMIP2B	NP_001274168.1	DUF2475	16..>45	CDD:431404	16/28 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..84		4/22 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	125..169		8/65 (12%)
CG18335	NP_610666.1	DUF2475	8..54	CDD:431404	21/46 (46%)
		DUF2475	271..>297	CDD:431404	7/28 (25%)