DRSC/TRiP Functional Genomics Resources

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Protein Alignment TYRO3 and dpr11

DIOPT Version :9

Sequence 1:NP_006284.2 Gene:TYRO3 / 7301 HGNCID:12446 Length:890 Species:Homo sapiens
Sequence 2:NP_001262320.1 Gene:dpr11 / 40800 FlyBaseID:FBgn0053202 Length:360 Species:Drosophila melanogaster


Alignment Length:258 Identity:70/258 - (27%)
Similarity:107/258 - (41%) Gaps:54/258 - (20%)


- Green bases have known domain annotations that are detailed below.


Human    29 ALASLLLPE----SAAAGL---KLMG-APVKLTVSQGQPVKLNCSVEGMEEPDIQWV--KDGAV- 82
            |..|.||||    ||.:||   .|.| |...:|...|....|.|.|:.:....:.|:  :||.: 
  Fly    96 AQVSSLLPEASALSATSGLVEPYLDGYATSNVTTQIGTHAYLPCRVKQLGNKSVSWIRLRDGHIL 160

Human    83 -----VQNLDQLYIPVS--EQHWIGFLSLKSVERSDAGRYWCQVEDGGETEISQPVWLTVEGVPF 140
                 |...||.::.:.  :::|.  |.:|.|:..|||.|.|||..  |.::|..|.|.|. ||.
  Fly   161 TVDRAVFIADQRFLAIKQPDKYWT--LQIKYVQARDAGSYECQVST--EPKVSARVQLQVV-VPR 220

Human   141 FTV--EPKDLAVPPNAPFQLSCEAVGPPEPVT-IVWWRGTTKIGGPAP------SPSVLNVTGVT 196
            ..:  || |..|...:...|.|...|..||.| |:|:.|..::...:.      .|::...:|..
  Fly   221 TEILGEP-DRYVKAGSNVVLRCIVRGALEPPTFIMWYHGAEQLAADSRRHRTQLDPNLPEASGEG 284

Human   197 QSTM---------------FSCEAHNLKGLASSRTATVHLQALPAAPFNITVTKLSSSNASVA 244
            |||:               ::|...|      |.:|||.|..:........||..:::..:.|
  Fly   285 QSTIGSLIIESAKKRDTGNYTCSPSN------SPSATVTLNIINGESSASAVTSSAATTRAYA 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TYRO3NP_006284.2 IG_like 49..135 CDD:214653 26/95 (27%)
IGc2 56..121 CDD:197706 21/74 (28%)
Ig2_Tyro3_like 141..220 CDD:143226 23/102 (23%)
IG_like 145..220 CDD:214653 22/96 (23%)
FN3 225..317 CDD:238020 3/20 (15%)
fn3 324..406 CDD:278470
PTKc_Tyro3 508..791 CDD:270659
Pkinase_Tyr 518..786 CDD:285015
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 815..837
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 851..871
dpr11NP_001262320.1 I-set 125..216 CDD:254352 26/94 (28%)
Ig 127..217 CDD:299845 26/93 (28%)
IG_like 227..320 CDD:214653 24/99 (24%)
IGc2 234..311 CDD:197706 16/82 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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